期刊論文/Journal Paper

1 (Kuo-Chu Lai)、謝蕙霞(Hsieh, Hui-Hsia)、(Yi-Liang Lu)、劉欣怡(Liu,Shin-Yi)、(Hai-Anh Ha)*、侯曼貞(Mann-Jen Hou)*,Design and Synthesis of Holu-7, a Quinazolinone Derivative With an Active Stereo Geometry and Polar 2,4-Dihydroxyphenyl Group, as a Selective Anticancer Agent,Chemical Biology & Drug Design,2025 Dec,106(6):e70209,SCI
2 謝蕙霞(Hsieh, Hui-Hsia)、吳天元(Wu, Tien-Yuan)、李宛怡(Lee, Wan-Yi)、陳綺華(Chen, Chi-Hua)、郭育紅(Kuo, Yu-Hung)、李鳳琴(Hong-Zin Lee)*、侯曼貞(Mann-Jen Hou)*,Effect of antihypertensive drugs on survival in patients with non-small cell lung cancer on epidermal growth factor receptor inhibitors,American Journal of Cancer Research,2025 Oct,15(10):4347-4359,SCI
3 (Yeh Chen)、侯曼貞(Mann-Jen Hou)、(Chen-Sheng Lin)、(Young-Sheng Chang)、(Zan-Yu Chen)、(Alena V. Koval’skaya)、蘇文琪(Wen-Chi Su)、(Inna P. Tsypysheva)*、林振文(Lin, Cheng-Wen)*,Assessing the inhibitory effects of some secondary amines, thioureas and 1,3-dimethyluracil conjugates of (-)-cytisine and thermopsine on the RNA-dependent RNA polymerase of SARS-CoV-1 and SARS-CoV-2,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2024 Nov,113():1-8,SCI
4 侯曼貞(Mann-Jen Hou)、蔡輔仁(Fuu-Jen Tsai)、賴奕如(I-Lu Lai)、曹哲維(Je-Wei Tsao)、江若華(Jo-Hua Chiang)、邱宇任(Yu-Jen Chiu)、呂幸芳(LU HSING-FANG)、阮于寧(Yu-Ning Juan)、楊家欣(Jai-Sing Yang)*、蔡士彰(Tsai, Shih-Chang)*,Efficacy of HMJ-38, a new quinazolinone analogue, against the gemcitabine-resistant MIA-PaCa-2 pancreatic cancer cells,BIOMEDICINE-TAIWAN,2023 Jul,():,Other
5 謝蕙霞(Hsieh, Hui-Hsia)、(Tien-Yuan Wu)、(Chi-Hua Chen)、(Yu-Hung Kuo)、侯曼貞(Mann-Jen Hou)*,Survival Outcomes of Calcium Channel Blocker Therapy in Patients With Non-Small Cell Lung Cancer Treated With Epidermal Growth Factor Receptor Inhibitors: A Retrospective Study,INTEGRATIVE CANCER THERAPIES,2023 Jun,22():1-9,SCI
6 謝蕙霞(Hsieh, Hui-Hsia)、(Tien-Yuan Wu)、(Chi-Hua Chen)、(Yu-Hung Kuo)、侯曼貞(Mann-Jen Hou)*,Survival outcomes of beta-blocker usage in HER2-positive advanced breast cancer patients: a retrospective cohort study,Therapeutic Advances in Drug Safety,2023 Jun,14():1-12,SCI
7 謝蕙霞(Hsieh, Hui-Hsia)、(Tien-Yuan Wu)、(Chi-Hua Chen)、(Yu-Hung Kuo)、侯曼貞(Mann-Jen Hou)*,Clinical impact of tetracyclines and/or proton pump inhibitors on the efficacy of epidermal growth factor receptor inhibitors in non‑small cell lung cancer: a retrospective cohort study,BMC CANCER,2023 Feb,23(1):151,SCI
8 侯曼貞(Mann-Jen Hou)、陳曄(Chen,Yeh)、(Chen-Sheng Lin)、(Lidia A. Baltina)、(Ju-Ying Kan)、(Yan-Ting Tsai)、(Yan-Tung Kiu)、賴學洲(Hsueh-Chou Lai)、(Lia A. Baltina)、(Svetlana F. Petrova)、林振文(Lin, Cheng-Wen)*,Glycyrrhizic Acid Derivatives Bearing Amino Acid Residues in the Carbohydrate Part as Dengue Virus E Protein Inhibitors: Synthesis and Antiviral Activity,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2022 Sep,23(18):10309,SCI
9 謝蕙霞(Hsieh, Hui-Hsia)、(Tien-Yuan Wu)、(Chi-Hua Chen)、侯曼貞(Mann-Jen Hou)*,Cost-effectiveness and clinical outcomes of intermittent/continuous proton pump inhibitors infusion in high bleeding risk of ulcers A retrospective observational cohort study,MEDICINE,2021 Dec,100(49):e28064,SCI
10 (Hai-Anh Ha)、侯曼貞(Mann-Jen Hou)*、楊家欣(Jai-Sing Yang)*,Molecular Dynamics Study of MJ-33 and Derivatives Designed as cKit Kinase Inhibitors,International Journal of Pharmacology,2021 Aug,17():144-155,SCI
11 (Lidia A. Baltina)、賴學洲(Hsueh-Chou Lai)、劉亞祁(Ya-Chi Liu)、黃素華(Su-Hua Huang)、侯曼貞(Mann-Jen Hou)、(Lia A. Baltina)、(Tagir R. Nugumanov)、(Sophia S. Borisevich)、(Leonard M. Khalilov)、(Svetlana F. Petrov)、(Sergey L. Khursan)、林振文(Lin Cheng Wen)*,Glycyrrhetinic acid derivatives as Zika virus inhibitors: Synthesis and antiviral activity in vitro,BIOORGANIC & MEDICINAL CHEMISTRY,2021 Jul,41():,SCI
12 Ha Hai Anh(HA HAI ANH)、楊家欣(Jai-Sing Yang)、蔡輔仁(Fuu-Jen Tsai)、李彰威(CHANG-WEI LI)、鄭奕帝(Yih-Dih Cheng)、李劍勇(JIANYONG LI)、侯曼貞(Mann-Jen Hou)*、邱宇任,Establishment of a Novel Temozolomide Resistant Subline of Glioblastoma Multiforme Cells and Comparative Transcriptome Analysis With Parental Cells,ANTICANCER RESEARCH,2021 Apr,41(5):2333-2347,SCI
13 Lidia A. Bal、侯曼貞(Mann-Jen Hou)、(Ya-Chi Liu)、(Young-Sheng Chang)、(Su-Hua Huang)、賴學洲(Hsueh-Chou Lai)、(Rimma M. Kondratenko)、(Svetlana F. Petrova)、(Marat S. Yunusov)、林振文(Lin Cheng Wen)*,Antiviral activity of glycyrrhizic acid conjugates with amino acid esters against Zika virus,VIRUS RESEARCH,2021 Mar,294():198290,SCI
14 (KUO-CHU LAI)、(YI-TING CHIA)、(LING-HUEI YIH)、呂翼良(YI-LIANG LU)、張士庭(Chang, Shih-Ting)、(ZI-XUAN HONG)、陳泰霖(Chen, Tai-Lin)*、侯曼貞(Mann-Jen Hou)*,Antitumor Effects of the Novel Quinazolinone Holu-12: Induction of Mitotic Arrest and Apoptosis in Human Oral Squamous Cell Carcinoma CAL27 Cells,ANTICANCER RESEARCH,2021 Jan,41(1):259-268,SCI
15 (HAI-ANH HA)、(JO-HUA CHIANG)、蔡輔仁(Fuu-Jen Tsai)、包大靝(Da-Tian Bau)、阮于寧(Yu-Ning Juan)、(YU-HSIANG LO)、侯曼貞(Mann-Jen Hou)*、楊家欣(Jai-Sing Yang)*,Novel quinazolinone MJ-33 induces AKT/mTOR-mediated autophagy-associated apoptosis in 5FU-resistant colorectal cancer cells,ONCOLOGY REPORTS,2020 Dec,():1-13,SCI
16 (Yu-Jen Chiu)、(Jo?Hua Chiang)、(Chih-Wei Fu)、侯曼貞(Mann-Jen Hou)、(Hai-Anh Ha)、郭盛助(Sheng-Chu kuo)、林楨智(Jen-Jyn Lin)、程景章(CHENG,CHING-CHANG)、蔡士彰(Shih-Chang Tsai)、(Yu?Shiang Lo)、阮于寧(Yu-Ning Juan)、鄭奕帝(Yih-Dih Cheng)、楊家欣(Jai-Sing Yang)*、蔡輔仁(Fuu-Jen Tsai)*,Analysis of COVID-19 prevention and treatment in Taiwan (Review),BIOMEDICINE-TAIWAN,2020 Dec,():,Other
17 陳清玉(Chen, Cing-Yu)、侯曼貞(Mann-Jen Hou)、蕭蓮如(Shiao, Lian-Ru)、黃家樂(Wong, Kar-Lok)、梁育民(Yuk-Man Leung)*、陳保羅(Chan, Paul)、蘇翔(Edmund Cheung So),Quercetin depletes intracellular Ca2+ stores and blunts ATP-triggered Ca2+ signaling in bEnd.3 endothelial cells.,FUNDAMENTAL & CLINICAL PHARMACOLOGY,2020 Apr,34(2):213-221,SCI
18 陳清玉(Chen, Cing-Yu)、侯曼貞(Mann-Jen Hou)、林文川(Wen-Chuan Lin)、黃家樂(Wong, Kar-Lok)、(Lian-Ru Shiao)、鄭嘉遜(Ka-Shun Cheng)、(Paul Chan)、梁育民(Yuk-Man Leung)*,Antagonism of Ca2+-sensing receptors by NPS 2143 is transiently masked by p38 activation in mouse brain bEND.3 endothelial cells,NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY,2019 Jul,392(7):823-832,SCI
19 游邦照(Bang-Jau You)、侯曼貞(Mann-Jen Hou)、陳立芸(Li-Yun Chen)、羅舒清(Shu-Ching Luo)、許博翔(Hsu po-hsing)、李鳳琴(Hong-Zin Lee)*,Fenofibrate induces human hepatoma Hep3B cells apoptosis and necroptosis through inhibition of thioesterase domain of fatty acid synthase,Scientific Reports,2019 Mar,9(1):3306-3306,SCI
20 (Ching-Ying Wang)、(Chen-Sheng Lin)、花俊宏(Chun-Hung Hua)、(Yu-Jen Jou)、(Chi-Ren Liao)、張永勳(Yuan-Shiun Chang)、萬磊(Lei Wan)、(Su-Hua Huang)、侯曼貞(Mann-Jen Hou)*、林振文(Lin Cheng Wen)*,Cis-3-O-p-hydroxycinnamoyl Ursolic Acid Induced ROS-Dependent p53-Mediated Mitochondrial Apoptosis in Oral Cancer Cells,Biomolecules & Therapeutics,2019 Jan,27(1):54-62,SCI
21 (Ching-Ying Wang)、侯曼貞(Mann-Jen Hou)、賴學洲(Hsueh-Chou Lai)、陳昭賢(Chen, Chao-Hsien)、(Pei-Jung Chang)、(Su-Hua Huang)、林振文(Lin, Cheng-Wen)*,Epigallocatechin-3-gallate inhibits the early stages of Japanese encephalitis virus infection,VIRUS RESEARCH,2018 Jun,253():140-146,SCI
22 邱宇任(YU-JEN CHIU)、侯曼貞(Hour, Mann-Jen)、金益安(YI-AN JIN)、呂啟誠(CHI-CHENG LU)、蔡輔仁(Tsai, Fuu-Jen)、陳泰霖(Chen, Tai-Lin)、馬旭(HSU MA)、阮于寧(Yu-Ning Juan)、楊家欣(Yang Jai-Sing)*,Disruption of IGF-1R signaling by a novel quinazoline derivative (HMJ-30) inhibits invasiveness and induces reverse epithelial-mesenchymal transition (EMT) process in osteosarcoma U-2 OS cells,INTERNATIONAL JOURNAL OF ONCOLOGY,2018 Jan,52():,SCI
23 (Chien-Yi Lu)、張益銍(Yi-Chih, Chang)、花俊宏(Chun-Hung Hua)、(Chieh Chuang)、(Su-Hua Huang)、(Szu-Hao Kung)、侯曼貞(Hour Mann-Jen)*、林振文(Lin Cheng Wen)*,Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2017 May,18(5):954,SCI
24 (Chien-Yi Lu)、侯曼貞(Hour Mann-Jen)、(Ching-Ying Wang)、(Su-Hua Huang)、(Wen-Xiang Mu)、(Yu-Chun Chang)、林振文(Lin Cheng Wen)*,Single-Round Infectious Particle Antiviral Screening Assays for the Japanese Encephalitis Virus,Viruses-Basel,2017 Apr,9(4):76,SCI
25 (Ching-Ying Wang)、(Chien-Yi Lu)、(Shih-Wen Li)、(Chien-Chen Lai)、花俊宏(Chun-Hung Hua)、(Su-Hua Huang)、林應如(Ying-Ju Lin)、侯曼貞(Hour Mann-Jen)*、林振文(Lin Cheng Wen)*,SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling,VIRUS RESEARCH,2017 Apr,235():58-66,SCI
26 (Ching-Ying Wang)、(An-Cheng Huang)、侯曼貞(Hour Mann-Jen)、(Su-Hua Huang)、(Szu-Hao Kung)、陳昭賢(Chao-Hsien Chen)、(I-Chieh Chen)、張永勳(Yuan Shiun Chang)、連金城(Lien Jin Cherng)*、林振文(Lin Cheng Wen)*,Antiviral potential of a novel compound CW-33 against Enterovirus A71 via inhibition viral 2A protease,Viruses-Basel,2015 Jun,7(6):3155-3171,SCI
27 (Wei-Ting Liu)、(Ching Chen)、(I-Chen Lu)、郭盛助(Sheng-Chu Kuo)、李國雄(Kuo-Hsiung Lee)、陳泰霖(Chen, Tai-Lin)、宋達樞、呂翼良、(Po-Wu Gean)*、侯曼貞(Hour Mann-Jen)*,MJ-66 induces malignant glioma cells G2/M phase arrest and mitotic catastrophe through regulation of cyclin B1/Cdk1 complex,NEUROPHARMACOLOGY,2014 Nov,86(/):219-227,SCI
28 (Han-Ching Lin)、(Tzu-Hung Lin)、(Ming-Yueh Wu)、(Yung-Cheng Chiu)、湯智昕(Tang Chih-Hsin)、侯曼貞(Hour Mann-Jen)、(Houng-Chi Liou)、(Huang-Ju Tu)、(Rong-Sen Yang)*、(Wen-Mei Fu)*,5-Lipoxygenase Inhibitors Attenuate TNF-α-Induced Inflammation in Human Synovial Fibroblasts,PLoS One,2014 Sep,9(9):e107890-e107890,SCI
29 侯曼貞(Hour Mann-Jen)、(Wei-Ting Liu)、(I-Chen Lu)、郭盛助(Sheng-Chu Kuo)、(Po-Wu Gean)*,Aggravated DNA damage as a basis for enhanced glioma cell killing by MJ-66 in combination with minocycline,American Journal of Cancer Research,2014 Sep,4(5):474-483,SCI
30 宋達樞(TA-SHU SONG)、謝右文(Yow-Wen Hsieh)、彭慶添(Ching-Tien Peng)、陳泰霖(Chen, Tai-Lin)、李鳳琴(Hong-Zin Lee)、鍾景光(Jing-Gung Chung)、侯曼貞(Hour Mann-Jen)*,Combined Versus Monotherapy or Concurrent Therapy for Treatment Of Thalassaemia,IN VIVO,2014 Jul,28():,SCI
31 江若華、楊家欣(Yang Jai-Sing)、呂啟誠、侯曼貞(Hour Mann-Jen)、劉國慶(KUO-CHING LIU)、林楨智(Jen-Jyn Lin)、林如華(JU-HWA, LIN)、(T-H Lee)*、鍾景光(Jing-Gung Chung)*,Effect of DNA damage response by quinazolinone analogue HMJ-38 on human umbilical vein endothelial cells: Evidence for gammaH2A.X and DNA-PK-dependent pathway,HUMAN & EXPERIMENTAL TOXICOLOGY,2014 Jun,33(6):590-601,SCI
32 呂啟誠(Chi-Cheng Lu)、楊家欣(Yang Jai-Sing)、江若華(Jo-Hua Chiang)、侯曼貞(Hour Mann-Jen)、(Kuei-Li Lin)、(Tsung-Han Lee)*、鍾景光(Jing-Gung Chung)*,Cell death caused by quinazolinone HMJ-38 challenge in oral carcinoma CAL 27 cells: dissections of endoplasmic reticulum stress, mitochondrial dysfunction and tumor xenografts,BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,2014 Mar,**(**):**-**,SCI
33 彭淑芬(Shu-Fen Peng)、李昭瑩(Lee Chao-Ying)、侯曼貞(Hour Mann-Jen)、蔡士彰(Shih-Chang Tsai)、郭代璜(DAIH-HUANG KUO)、陳福安(FU-AN CHEN)、謝博銓(PO-CHUEN SHIEH)、楊家欣(Yang Jai-Sing)*,Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway,INTERNATIONAL JOURNAL OF ONCOLOGY,2014 Jan,(44):238-246,SCI
34 廖容君(Jung-Chun Liao)、張文德(Wen-Te Chang)、藍于琁(Lan Yu Hsuan)、侯曼貞(Hour Mann-Jen)、李鳳琴(Hong-Zin Lee)*,Application of proteomics to identify the target molecules involved in Lonicera japonica-induced photokilling in human lung cancer CH27 cells,BMC Complementary and Alternative Medicine,2013 Oct,13(1):244-256,SCI
35 (Kang KH)、(Liou HH)、侯曼貞(Hour Mann-Jen)、(Liou HC)、(Fu WM)*,Protection of dopaminergic neurons by 5-lipoxygenase inhibitor,NEUROPHARMACOLOGY,2013 Oct,73(1):380-387,SCI
36 (Ting WC)、陳璐敏(Lu-Min Chen)、(Huang LC)、侯曼貞(Hour Mann-Jen)、藍于琁(Lan Yu Hsuan)、李鳳琴(Hong-Zin Lee)、游邦照(Bang-Jau You)、張大元(Ta-Yuan Chang)、鮑柏穎(Bo-Ying Bao)*,Impact of interleukin-10 gene polymorphisms on survival in patients with colorectal cancer,JOURNAL OF KOREAN MEDICAL SCIENCE,2013 Sep,28(9):1302-1306,SCI
37 侯曼貞(Hour Mann-Jen)*、(K H Lee)、陳泰霖(Chen, Tai-Lin)、(K T Lee)、(Yu Zhao)、李鳳琴(Hong-Zin Lee)*,Molecular modeling, synthesis, cytotoxicity and anti-tumor mechanisms of 2-aryl-6-substituted quinazolinones as dual-targeted anticancer agents,BRITISH JOURNAL OF PHARMACOLOGY,2013 Aug,169(7):1574-1586,SCI
38 (Kang KH)、(Ling TY)、(Liou HH)、(Huang YK)、侯曼貞(Hour Mann-Jen)、(Liou HC)、(Fu WM)*,Enhancement role of host 12/15-lipoxygenase in melanoma progression,EUROPEAN JOURNAL OF CANCER,2013 Aug,49(12):2747-2759,SCI
39 陳慧婕(Hui-Jye Chen)、(YI-LIN JIANG)、(CHUNG-MING LIN)、蔡士彰(Shih-Chang Tsai)、彭淑芬(Shu-Fen Peng)、(SHINJI FUSHIYA)、侯曼貞(Hour Mann-Jen)*、楊家欣(Yang Jai-Sing)*,Dual inhibition of EGFR and c-Met kinase activation by MJ-56 reduces metastasis of HT29 human colorectal cancer cells,INTERNATIONAL JOURNAL OF ONCOLOGY,2013 Jul,43(1):141-150,SCI
40 侯曼貞(Hour Mann-Jen)、黃素華(Su-Hua Huang)、張清堯(Ching-Yao Chang)、林妍冠(Yen-Kuan Lin)、王靜瑩(Ching-Ying Wang)、張永勳(Yuan Shiun Chang)、林振文(Lin Cheng Wen)*,Baicalein, ethyl acetate and chloroform extracts of Scutellaria baicalensis inhibit the neuraminidase activity of pandemic 2009 H1N1 and seasonal influenza A viruses,Evidence-based Complementary and Alternative Medicine,2013 Jun,2013(2013):750803,SCI
41 (Jo-Hua Chiang)、楊家欣(Yang Jai-Sing)、(Chi-Cheng Lu)、侯曼貞(Hour Mann-Jen)、張淑貞(Shu-Jen Chang)、李宗翰(Tsung-Han Lee)*、鍾景光(Jing-Gung Chung)*,Newly synthesized quinazolinone HMJ-38 suppresses angiogenetic responses and triggers human umbilical vein endothelial cell apoptosis through p53-modulated Fas/death receptor signaling,TOXICOLOGY AND APPLIED PHARMACOLOGY,2013 Jun,269(2):150-162,SCI
42 侯曼貞(Hour Mann-Jen)、(Lee KT)、吳永昌(Yang-Chang Wu)、(Wu CY)、游邦照(Bang-Jau You)、陳泰霖(Chen, Tai-Lin)、李鳳琴(Hong-Zin Lee)*,A novel antitubulin agent, DPQZ, induces cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation,ARCHIVES OF TOXICOLOGY,2013 May,87(5):835-846,SCI
43 (Xiao-Feng Wang)、(Xing-Tao Tian)、(Emika Ohkoshi)、(Bingjie Qin)、(Yi-Nan Liu)、(Pei-Chi Wu)、侯曼貞(Hour Mann-Jen)、洪欣儀(Hsin-Yi Hung)、(Keduo Qian)、(Rong Huang)、(Kenneth F. Bastow)、(William P. Janzen)、(Jian Jin)、(Susan L. Morris-Natschke)、李國雄(Kuo-Hsiung Lee)、(Lan Xie)*,Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2012 Oct,22(19):6224-6228,SCI
44 侯曼貞(Hour Mann-Jen)、蔡士彰(Shih-Chang Tsai)、吳錫金(Wu,Hsi-Chin)、林孟崴(MENG-WEI LIN)、鍾景光(Jing-Gung Chung)、吳金濱(Jin Bin Wu)、江若華(JO-HUA CHIANG)、(MINORU TSUZUKI)、楊家欣(Yang Jai-Sing)*,Antitumor effects of the novel quinazolinone MJ-33: Inhibition of metastasis through the MAPK, AKT, NF-κB and AP-1 signaling pathways in DU145 human prostate cancer cells,INTERNATIONAL JOURNAL OF ONCOLOGY,2012 Oct,41(4):1513-1519,SCI
45 呂啟誠(Lu CC)、楊家欣(Yang Jai-Sing)、江若華(Chiang JH)、侯曼貞(Hour Mann-Jen)、(Kuei-Li Lin)、林楨智(Jen-Jyn Lin)、黃雯雯(Wenwen Huang)、(Minoru Tsuzuki)、李宗翰(Tsung-Han Lee)*、鍾景光(Jing-Gung Chung)*,Novel Quinazolinone MJ-29 Triggers Endoplasmic Reticulum Stress and Intrinsic Apoptosis in Murine Leukemia WEHI-3 Cells and Inhibits Leukemic Mice,PLoS One,2012 May,7(5):e36831-e36831,SCI
46 宋達樞(Ta-Shu Song)、謝右文(Yow-Wen Hsieh)、彭慶添(Ching-Tien Peng)、(Cheng-Hsiung Liu)、陳泰霖(Chen, Tai-Lin)、侯曼貞(Hour Mann-Jen)*,Development of a fast LC-MS/MS assay for the determination of deferiprone in human plasma and application to pharmacokinetics,BIOMEDICAL CHROMATOGRAPHY,2012 Feb,2012(26):1575-1581,SCI
47 邱宇任(Yu-Jen Chiu)、侯曼貞(Hour Mann-Jen)、呂啟誠(Chi-Cheng Lu)、鍾景光(Jing-Gung Chung)、郭盛助(Sheng-Chu Kuo)、黃雯雯(Wenwen Huang)、陳慧婕(Hui-Jye Chen)、Yi-An Jin(金益安)、楊家欣(Yang Jai-Sing)*,Novel Quinazoline HMJ-30 Induces U-2 OS Human Osteogenic Sarcoma Cell Apoptosis Through Induction of Oxidative Stress and Up-Regulation of ATM/p53 Signaling Pathway,JOURNAL OF ORTHOPAEDIC RESEARCH,2011 Sep,29(9):1448-1456,SCI
48 陳冠廷(KUAN-TIN CHEN)、侯曼貞(Hour Mann-Jen)、蔡士彰(Shih-Chang Tsai)、鍾景光(Jing-Gung Chung)、郭盛助(Sheng-Chu Kuo)、呂啟誠(CHI-CHENG LU)、邱宇任(YU-JEN CHIU)、莊貽煊(YI-HSUAN CHUANG)、楊家欣(Yang Jai-Sing)*,The novel synthesized 6-fluoro-(3-fluorophenyl)-4-(3-methoxyanilino)quinazoline (LJJ-10) compound exhibits anti-metastatic effects in human osteosarcoma U-2 OS cells through targeting insulin-like growth factor-I receptor,INTERNATIONAL JOURNAL OF ONCOLOGY,2011 Sep,39(3):611-619,SCI
49 吳永昌、侯曼貞(Hour Mann-Jen)、梁永昌、吳吉育、劉文治、張育豪、李鳳琴(Hong-Zin Lee)*,2-(Naphthalene-1-yl)-6-pyrrolidinyl-4-quinazolinone inhibits skin cancer M21 cell proliferation through aberrant expression of microtubule and cell cycle,JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS,2011 Sep,338(3):942-951,SCI
50 侯曼貞(Hour Mann-Jen)*、楊家欣(Yang Jai-Sing)、陳泰霖(Chen, Tai-Lin)、陳冠廷(Kuan-Tin Chen)、郭盛助(Sheng-Chu Kuo)、鍾景光(Jing-Gung Chung)、呂啟誠(Chi-Cheng Lu)、陳佳儀(Chia-Yi Chen)、莊貽媗(Yi-Hsuan Chuang),The synthesized novel fluorinated compound (LJJ-10) induces death receptor- and mitochondriadependent apoptotic cell death in the human osteogenic sarcoma U-2 OS cells,EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,2011 Jul,46(7):2709-2721,SCI
51 梁育民*、鄒毅寰(Yi-Huan Tsou)、郭昌鑫(Chang-Shin Kuo)、(Shang-Ying Lin)、(Pau-Yen Wu)、侯曼貞(Hour Mann-Jen)、郭悅雄,Arylnaphthalene lignans from Taiwania cryptomerioides as novel blockers of voltage-gated K+ channels,PHYTOMEDICINE,2010 Dec,18():,SCI
52 李鳳琴(Hong-Zin Lee)*、楊文惠(Yang, Wen-Hui)、侯曼貞(Hour Mann-Jen)、(Chi-Yu Wu)、彭文煌(Wen-Huang Peng)、鮑柏穎(Bo-Ying Bao)、(Ping-Hsiu Han)、包大靝(Da-Tian Bau)*,Photodynamic activity of aloe-emodin induces resensitization of lung cancer cells to anoikis,European Journal of Pharmacology,2010 Sep,648(1-3):50-58,SCI
53 楊家欣(Yang Jai-Sing)、侯曼貞(Hour Mann-Jen)、黃雯雯(Wenwen Huang)、林奎利、郭盛助(Sheng-Chu Kuo)*、鍾景光(Jing-Gung Chung)*,MJ-29 inhibits tubulin polymerization, induces mitotic arrest and triggers apoptosis via CDK1-mediated Bcl-2 phosphorylation in human leukemia U937 cells,JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS,2010 May,334(2):477-488,SCI
54 梁永昌(Leung Wing-Cheung)、侯曼貞(Hour Mann-Jen)、張文德(Wen-Te Chang)、吳永昌、賴妙英(Miao-Ying Lai)、(M.-Y. Wang)、李鳳琴(Hong-Zin Lee)*,P38-associated pathway involvement in apoptosis induced by photodynamic therapy with Lonicera japonica in human lung squamous carcinoma CH27 cells.,FOOD AND CHEMICAL TOXICOLOGY,2008 Nov,46(11):3389-3400,SCI
55 連金城(Lien Jin Cherng)*、吳啟瑞(Chi-Rei Wu)、侯曼貞(Hour Mann-Jen)、黃麗嬌(Li-Jiau Huang)、(Tur-Fu Huang)、郭盛助(Sheng-Chu Kuo),Synthesis of 2,3-Disubstituted 1,4-naphthoquinones as Antiplatelet Agents,ARCHIV DER PHARMAZIE,2008 Aug,341(10):639-644,SCI
56 (Chia-Chia Chao)、(Jeffrey Shieh)、郭盛助(Sheng-Chu Kuo)、吳柏蒼(Bor-Tsang Wu)、侯曼貞(Hour Mann-Jen)*、梁育民*,HMJ-53A accelerates slow inactivation gating of voltage-gated K(+) channels in mouse neuroblastoma N2A cells.,NEUROPHARMACOLOGY,2008 Mar,54(2008):1128-1135,SCI
57 (W.C. Lueng)、林靜茹、侯曼貞、楊文惠、(M.Y. Wang)、李鳳琴(Hong-Zin Lee)*,Kaempferol induces apoptosis in human lung non-small carcinoma cells accompanies by an induction of antioxidant enzymes,FOOD AND CHEMICAL TOXICOLOGY,2007 Oct,10(45):2005-2013,SCI
58 賴妙英(Miao-Ying Lai)、侯曼貞、梁永昌、楊文惠(Yang, Wen-Hui)、李鳳琴(Hong-Zin Lee)*,Chaperones are the target in aloe-emodin-induced human lung nonsmall carcinoma H460 cell apoptosis,European Journal of Pharmacology,2007 Jul,573(573):1-10,SCI
59 侯曼貞*、楊家欣、連金城、郭盛助(Sheng-Chu Kuo)、黃麗嬌(Li-Jiau Huang),Synthesis and cytotoxicity of 6-pyrrolidinyl-2-(2-substituted phenyl)-4-quinazolinones,JOURNAL OF THE CHINESE CHEMICAL SOCIETY,2007 Jun,(54):785-790,SCI
60 (Chiang, K.-C.)、翁豐富(Wong, Fung Fuh)、張誌祥、侯曼貞、(Wang, Y.-L.)、(Wen, S.-B.)、(Yeh, M.-Y.),Synthesis and Characterization of 1,3,4-Oxadiazole-Triazolopyridinone Hybrid Derivatives as the New Blue-Greenish Photoluminescent Materials,JOURNAL OF HETEROCYCLIC CHEMISTRY,2007 Apr,(44):591-596,SCI
61 侯曼貞、連金城、(Cheng H. W.)、(Liu C. H.)、蔡輝彥(Huei-Yann Tsai)、賴振榕(Lai Zhen Rong)*,The Drug-Free-Adolescent Drive via Education at the Elementary Schools—Outcomes Evaluation through the Post-class Survey in Taichung (the second semester in 2004),Formosa Journal of Clinical Pharmacy,2007 Mar,14(3):15-32,Other
62 楊家欣、侯曼貞、郭盛助、黃麗嬌、李妙蓉*,Selective Induction of G2/M Arrest and Apoptosis in HL-60 by a Potent Anticancer Agent, HMJ-38,ANTICANCER RESEARCH,2004 May,24(3a):1769-1778,SCI
63 (Ting-Chia Ko)、侯曼貞、連金城、(Che-Ming Teng)、(Kuo-Hsiung Lee)、郭盛助(Sheng-Chu Kuo)、黃麗嬌(Li-Jiau Huang)*,Synthesis of 4-Alkoxy-2-phenylquinoline Derivatives as Potent Antiplatelet Agents,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2001 Nov,11(11):279-282,SCI
64 (Yi Xia)、(Zheng-Yu Yang)、侯曼貞、郭盛助(Sheng-Chu Kuo)、(Peng Xia)、(Kenneth F. Bastow)、(Yuka Nakanishi)、(Priya Nampoothiri)、(Torben Hackl)、(Ernest Hamel),Antitumor Agents. Part 204: Synthesis and Biological Evaluation of Substituted 2-Aryl Quinazolinones,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2001 ,(11):1193-1196,SCI
65 侯曼貞、黃麗嬌(Li-Jiau Huang)、(Che-Ming Teng)、郭盛助(Sheng-Chu Kuo)*,Synthesis and Antiplatelet Activity of Alkoxy Derivatives of 2-Phenylquinazolines,中華藥學雜誌,2000 ,(52):167-177,Other
66 侯曼貞、黃麗嬌(Li-Jiau Huang)、郭盛助(Sheng-Chu Kuo)、(Yi Xia)、(Kenneth Bastow)、(Yuka Nakanishi)、(Ernest Hamel)、(Kuo-Hsiung Lee*)*,6-Alkylamino- and 2,3-Dihydro-3'-methoxy-2-phenyl-4-quinazolinones and Related Compounds: Their Synthesis, Cytotoxicity, and Inhibition of Tubulin Polymerization.,JOURNAL OF MEDICINAL CHEMISTRY,2000 ,23(43):4479-4487,SCI