學術研究成果/Publication
基本資料/Profiles
姓名/Name: 黃俊瑩 性別/Gender:
英文姓名/
English Name:
Huang, Chun-Yin 英文縮寫/
Abbreviation:
Huang, C-Y
任職單位/
Affiliation:
1.生技製藥暨食品科學院營養學系(副教授) / Department of Nutrition(Associate Professor)
Email: chuang@mail.cmu.edu.tw
研究專長/Fields of Specialty
1﹒ 訊息傳遞與癌症
2﹒ 代謝症候群
3﹒ Adipocyte Differentiation
4﹒ Cancer and Metabolism
 
期刊論文/Journal Paper
(作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄)
SCI論文 鄭宇伸(Yu-Shen Cheng)、盧沛旻(Pei-Min Lu)、黃俊瑩(Huang, Chun-Yin)、吳佳娟(Wu, Jia-Jiuan)*,Encapsulation of lycopene with lecithin and α-tocopherol by supercritical antisolvent process for stability enhancement,JOURNAL OF SUPERCRITICAL FLUIDS,2017 Dec,130():246-252
SCI論文 黃俊瑩(Huang, Chun-Yin)、謝念祖(Nien-Tsu Hsieh)、(Chun-I Li)、(Yu-Ting Weng)、(Hsiao-Sheng Liu)、(Ming-Fen Lee)*,MED28 regulates epithelial–mesenchymal transition through NFkB in human breast cancer cells,JOURNAL OF CELLULAR PHYSIOLOGY,2017 Jun,232(6):1337-1345
SCI論文 詹前毅(Chien-Yi Chan)、(Shih-Yi Huang)、(Jim Jinn-Chyuan Sheu)、(Mendel M. Roth)、周義泰(I-Tai Chou)、連家賢(Chia-Hsien Lien)、(Ming-Fen Lee)*、黃俊瑩(Huang, Chun-Yin)*,Transcription factor HBP1 is a direct anti-cancer target of transcription factor FOXO1 in invasive oral cancer,Oncotarget,2017 Jan,8(9):14537-14548
SCI論文 詹前(Chien-Yi Chan)、余萍(Ping Yu)、張豐姿(Feng-Tzu Chang)、陳咨樺(Zih-Hua Chen)、(Ming-Fen Lee)、黃俊瑩(Huang, Chun-Yin)*,Transcription Factor HMG Box-containing Protein 1 (HBP1) Modulates Mitotic Clonal Expansion (MCE) during Adipocyte Differentiation,JOURNAL OF CELLULAR PHYSIOLOGY,2017 ,():
Other論文 詹前毅(Chien-Yi Chan)、連家賢(Chia-Hsien Lien)、(Min-Hsiung Pan)、黃俊瑩(Huang, Chun-Yin)*,Quercetin suppresses cellular migration and invasion in human head and neck squamous cell carcinoma (HNSCC),BioMedicine,2016 Sep,6(3):10-15
SCI論文 (Ming-Fen Lee)*、謝念祖(Nien-Tsu Hsieh)、黃俊瑩(Huang, Chun-Yin)、(Chun-I Li),All trans-retinoic acid mediates MED28/HMG box-containing protein 1(HBP1)/β-catenin signaling in human colorectal cancer cells,JOURNAL OF CELLULAR PHYSIOLOGY,2016 Aug,231(8):1796-1803
SCI論文 黃俊瑩(Huang, Chun-Yin)、謝念祖(Nien-Tsu Hsieh)、(Min-Hsiung Pan)、(Chun-I Li)、周毓軒(Yu-Hsuan Chou)、(Yi-Siou Chiou)、(Ming-Fen Lee)*,Resveratrol and pterostilbene regulate MED28 (magicin/EG1) expression and cell growth in MCF7 human breast cancer cells,Journal of Functional Foods,2015 Jan,12():158-167
SCI論文 詹前毅(Chien-yi Chan)、蒙美津(Mei-chin Mong)、劉文虎(Wen-hu Liu)、黃俊瑩(Huang, Chun-Yin)、殷梅津(YIN, MEI-CHIN)*,Three pentacyclic triterpenes protect H9c2 cardiomyoblast cells against high glucose induced injury,FREE RADICAL RESEARCH,2014 Apr,48(4):402-411
SCI論文 黃俊瑩(Huang, Chun-Yin)、詹前毅(Chien-Yi Chan)、周義泰(I-Tai Chou)、連家賢(Chia-Hsien Lien)、洪筱琪(Hsiao-Chi Hung)、(Ming-Fen Lee)*,Quercetin induces growth arrest through activation of FOXO1 transcription factor in EGFR-overexpressing oral cancer cells,JOURNAL OF NUTRITIONAL BIOCHEMISTRY,2013 Sep,24(9):1596-1603
SCI論文 (Ming-Fen Lee)、(Chien-Yi Chan)、(Hsiao-Chi Hung)、(I-Tai Chou)、(Amy S Yee)、黃俊瑩(Huang, Chun-Yin)*,N-acetylcysteine (NAC) inhibits cell growth by mediating the EGFR/Akt/HMG box-containing protein 1 (HBP1) signaling pathway in invasive oral cancer,ORAL ONCOLOGY,2013 Feb,49(2):129-135
SCI論文 黃俊瑩(Huang, Chun-Yin)、(Yu-Hsuan Chou,)、(Nien-Tsu Hsieh)、(Hsin-Hung Chen)、(Ming-Fen Lee)*,MED28 Regulates MEK1-dependent Cellular Migration in Human Breast Cancer Cells,JOURNAL OF CELLULAR PHYSIOLOGY,2012 Dec,227(12):3820-3827
SCI論文 李宗貴(Chong-Kuei Lii)、黃俊瑩(Huang, Chun-Yin)、陳暉雯(Haw-Wen Chen)、(Mun-Yew Chow)、(Yu-Ru Lin)、(Chin-Shiu Huang)、蔡佳文(Chia-Wen Tsai)*,Diallyl trisulfide suppresses the adipogenesis of 3T3-L1 preadipocytes through ERK activation,FOOD AND CHEMICAL TOXICOLOGY,2012 Mar,50():478-484
SCI論文 (Wang, Weibin)、(Pan, Kewu)、(Chen, Yifan)、黃俊瑩(Huang, Chun-Yin)、(Zhang, Xiaowei)*,The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression,NUCLEIC ACIDS RESEARCH,2012 Feb,40(3):981-995
SCI論文 姚賢宗(Hsien-Tsung Yao)*、(Mei-Ning Luo)、(Lang-Bang Hung)、(Meng-Tsan Chiang)、(Jia-Hsuan Lin)、李宗貴(Chong-Kuei Lii)、黃俊瑩(Huang, Chun-Yin)*,Effects of chitosan oligosaccharides on drug-metabolizing enzymes in rat liver and kidneys.,FOOD AND CHEMICAL TOXICOLOGY,2012 Feb,50(5):1171-1177
SCI論文 黃俊瑩(Huang, Chun-Yin)、(Chia-Yu Lin)、蔡佳文(Chia-Wen Tsai)、殷梅津(YIN, MEI-CHIN)*,Inhibition of cell proliferation, invasion and migration by ursolic acid in human lung cancer cell lines,TOXICOLOGY IN VITRO,2011 Sep,25(-):1274-1280
SCI論文 許游章(You-Cheng Hseu)、吳啟瑞(Chi-Rei Wu)、(HW Chang)、K.J.S. Kumar、林民昆(Lin, Ming-Kuem)、陳智聖(CS Chen)、左欣如(HJ Cho)、黃俊瑩(Huang, Chun-Yin)、黃志揚(Chih-Yang Huang)、李鳳琴(Hong-Zin Lee)、謝文聰(Hsieh Wen-Tsong)、鍾景光(Jing-Gung Chung)、(HM Wang)、楊新玲(Yang Hsin-ling)*,Inhibitory effects of Physalis angulata on tumor metastasis and angiogenesis,JOURNAL OF ETHNOPHARMACOLOGY,2011 May,135(-):762-771
SCI論文 陳姤君(Gou-Chun Chen)、黃俊瑩(Huang, Chun-Yin)、張美瑜(Mei-Yu Chang)、陳紀樺(Chi-Hua Chen)、陳秀雯(Shiow-Wen Chen)、黃青真(Ching-jang Huang)、趙蓓敏(Pei-Min Chao)*,Two unhealthy dietary habits featured a high fat content and a sucrose-containing beverages intake, alone or in combination, on inducing metabolic syndrome in Wistar rats and C57BL/6J mice,METABOLISM-CLINICAL AND EXPERIMENTAL,2011 Feb,60(2):155-164
SCI論文 (CHUN-CHE LIN)、黃俊瑩(Huang, Chun-Yin)、(MEI-CHIN MONG)、(CHIEN-YI CHAN)、殷梅津(YIN, MEI-CHIN)*,Antiangiogenic Potential of Three Triterpenic Acids in Human Liver Cancer Cells,JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2011 Jan,59(1):755-762
SCI論文 黃俊瑩(Huang, Chun-Yin)、林毓舜(Yu-Shun Lin)、陳姤君(Gou-Chun Chen)、黃惠玲(Hui-Ling Huang)、莊舒涵(Shu-Han Chuang)、趙蓓敏(Pei-Min Chao)*,Upregulation of Lipogenesis and Protein Tyrosine Phosphatase-1B Expression in the Liver of Wistar Rats with Metabolic Syndrome Chronically Induced by Drinking Sucrose Water,ANNALS OF NUTRITION AND METABOLISM,2010 Nov,57(2):169-176
SCI論文 (Sheng-lei Yan)、黃俊瑩(Huang, Chun-Yin)、(Shwu-tzy Wu)、殷梅津(YIN, MEI-CHIN)*,Oleanolic acid and ursolic acid induce apoptosis in four human liver cancer cell lines,TOXICOLOGY IN VITRO,2010 Mar,24():842-848
SCI論文 林佳育(CHIA-YU LIN)、黃晉修(CHIN-SHIU HUANG)、黃俊瑩(Huang, Chun-Yin)、殷梅津(YIN, MEI-CHIN)*,Anti-coagulatory, Anti-inflammatory and Anti-oxidative Effects of Protocatechuic Acid in Diabetic Mice,JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2009 Aug,(57):6661-6667
SCI論文 (Paulson KE)、(Rieger-Christ K)、(McDevitt MA)、(Kuperwasser C)、(Kim J)、(Unanue VE)、(Zhang X)、(Hu M)、(Ruthazer R)、(Berasi SP)、黃俊瑩(Huang, Chun-Yin)、(Giri D)、(Kaufman S)、(Dugan JM)、(Blum J)、(Netto G)、(Wazer DE)、(Summerhayes IC)、(Yee AS)*,Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer,CANCER RESEARCH,2007 Jul,67(13):6136-6145
SCI論文 黃俊瑩(Huang, Chun-Yin)、(Beliakoff J)、(Li X)、(Lee J)、(Li XM)、(Sharma M)、(Lim B)、(Sun Z),A novel PIAS-like Protein, hZimp7, enhances androgen receptor-mediated transcription and interacts with the SWI/SNF-like BAF complexes,MOLECULAR ENDOCRINOLOGY,2005 Dec,19(12):2915-2929
SCI論文 (Yee AS)*、(Paulson EK)、(McDevitt MA)、(Rieger-Christ K)、(Summerhayes I)、(Berasi SP)、(Kim J)、黃俊瑩(Huang, Chun-Yin)、(Zhang X.),The HBP1 transcriptional repressor and the p38 MAP kinase; unlikely partners in G1 regulation and tumor suppression,GENE,2004 Jul,336(1):1-13
SCI論文 (Sharma M)、(Li X)、(Wang Y)、(Zarnegar M)、黃俊瑩(Huang, Chun-Yin)、(Palvimo JJ)、(Lim B)、(Sun Z)*,hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci,EMBO JOURNAL,2003 Nov,17(22):6101-6114
SCI論文 (Xiu M)、(Kim J)、(Sampson E)、黃俊瑩(Huang, Chun-Yin)、(Davis RJ)、(Paulson KE)、(Yee AS),The transcriptional repressor HBP1 is a target of the p38 mitogen-activated protein kinase pathway in cell cycle regulation,MOLECULAR AND CELLULAR BIOLOGY,2003 ,23(23):8890-8901
 
研討會論文/Conference Papers
(發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目)
1﹒ Transcription Factor HMG box-Containing Protein 1 (HBP1) Mediates Anti-cancer Efficacy of Erlotinib in Oral Cancer,BIT’s 10th Annual World CANCER CONGRESS-2017,Barcelona, Spain,2017.5.19 ~ 2017.5.21,
2﹒ MED28 Regulates Proinflammatory Cytokine-induced Epithelial–Mesenchymal Transition and Invasion in Human Breast Cancer Cells,Experimental Biology 2017,Chicago, IL, USA,2017.4.22 ~ 2017.4.26,
3﹒ MED28 Mediates Glucose Metabolism in Human Colorectal Cancer Cells,Experimental Biology 2017,Chicago, IL, USA,2017.4.22 ~ 2017.4.26,
4﹒ MED28 regulates TNFa- and CoCl2-mediated migration and invasion in human non-small cell lung cancer (NSCLC) cells,EB (Experimental Biology) 2016,San Diego, USA,2016.4.2 ~ 2016.4.6,
5﹒ Transcription factor HMG box-containing protein 1 (HBP1) modulates mitotic clonal expansion (MCE) during adipocyte differentiation,EB (Experimental Biology) 2016,San Diego, USA,2016.4.2 ~ 2016.4.6,
6﹒ Vitamin D attenuates MED28-mediated cell growth and migration in human colon cancer cells,EB (Experimental Biology) 2016,San Diego, USA,2016.4.2 ~ 2016.4.6,
7﹒ HMG box-containing protein 1 (HBP1) modulates matrix metalloproteinase-13 (MMP-13)-mediated cellular migration and invasion in oral cancer,EB (Experimental Biology) 2016,San Diego, USA,2016.4.2 ~ 2016.4.6,
8﹒ 超臨界二氧化碳抗溶沉澱包覆茄紅素以延緩氧化,第41屆台灣營養學會年會暨學術研討會-癌症預防與營養照護推廣,嘉南藥理大學,2015.5.22 ~ 2015.5.23,
9﹒ MED28 mediates Wnt/β-catenin signaling through HMG box-containing protein (HBP1) in human colon cancer cells,Experimental Biology 2014,San Diego, USA,2014.4.26 ~ 2014.4.30,
10﹒ MED28 regulates the development of epithelial-mesenchymal transition and invasion in human lung cancer cells,Experimental Biology 2014,San Diego, USA,2014.4.26 ~ 2014.4.30,
11﹒ 轉錄因子FOXO1調結槲皮素(Quercetin)抑制口腔癌細胞的侵襲轉移,第39屆營養年會暨學術研討會,中國醫藥大學,2013.5.24 ~ 2013.5.25,
12﹒ Transcription Factor HBP1 Regulates Cellular Migration and Invasion in Oral Cancer cells,第28屆生物醫學聯合學術年會,國防醫學院,2013.3.23 ~ 2013.3.24,
13﹒ HMG box-containing protein 1 (HBP1) participates in the antitumor effect of N-acetylcysteine (NAC) in invasive oral cancer,2012 AACR Annual Meeting,Chicago, IL, USA,2012.3.31 ~ 2012.4.4,
14﹒ MED28 (magicin/EG-1) modulates MEK1 (MAP2K1)-dependent cellular migration in human breast cancer cells,2012 AACR Annual Meeting,Chicago, IL, USA,2012.3.31 ~ 2012.4.4,
15﹒ HMG box-containing protein 1 (HBP1) is a direct target of transcription factor FOXO1 in invasive oral cancer,2012 AACR Annual Meeting,Chicago, IL, USA,2012.3.31 ~ 2012.4.4,
16﹒ MED28 (Magicin) Regulates Migration and Cell Cycle Progression in MCF-7 Human Breast Cancer Cells,Experimental Biology 2011,Washington, DC USA,2011.4.9 ~ 2011.4.13,
17﹒ 槲皮素(Quercetin)抑制口腔癌細胞生長的關鍵標的-FOXO-HBP1路徑,第36屆營養年會暨學術研討會,輔仁大學,2010.5.21 ~ 2010.5.22,
18﹒ Transcription factor HBP1 functions as a regulator of adipocyte differentiation,Experimental Biology 2010,Anaheim, California, USA,2010.4.24 ~ 2010.4.28,
19﹒ 轉錄因子HBP1階段性調控3T3-L1的脂質生合成,第35屆營養年會暨學術研討會,靜宜大學,2009.5.22 ~ 2009.5.23,
20﹒ N-acetylcysteine(NAC)藉由活化轉錄抑制因子HBP1抑制口腔癌上皮生長因子受體(EGFR)和Wnt訊息傳遞路徑,第35屆營養年會暨學術研討會,靜宜大學,2009.5.22 ~ 2009.5.23,
21﹒ 轉錄抑制因子HBP1經由對氧化還原平衡的調控抑制MDA-MB-231乳癌細胞配體依賴型之上皮生長因子受體的訊息傳遞,第34屆營養年會暨學術研討會,義守大學,2008.5.30 ~ 2008.5.31,
22﹒ Transcriptional repressor HBP1 inhibition of EGFR signaling: regulation of ligand-stimulated reactive oxygen species generation,97th AACR Annual Meeting 2006,Washington DC, USA,2006.4.1 ~ 2006.4.5,
 
研究計畫/Research Grant
(研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,研究經費,計畫期間)
1﹒ 個別型,MOST 105-2320-B-039-044-MY2,黃俊瑩(Huang, Chun-Yin),科技部,轉錄因子HBP1調節脂肪細胞分化、胰島素阻抗、以及連結胰島素阻抗與癌細胞惡化之機制探討,$1183000,2017.8.1 ~ 2018.7.31
2﹒ 個別型,MOST 103-2320-B-039 -031-MY3,黃俊瑩(Huang, Chun-Yin),科技部,探討葡萄糖代謝影響口腔癌增生與轉移的分子機制,$1008000,2016.8.1 ~ 2017.7.31
3﹒ 個別型,MOST 105-2320-B-039-044-MY2,黃俊瑩(Huang, Chun-Yin),科技部,轉錄因子HBP1調節脂肪細胞分化、胰島素阻抗、以及連結胰島素阻抗與癌細胞惡化之機制探討,$1178000,2016.8.1 ~ 2017.7.31
4﹒ 個別型,MOST 103-2320-B-039 -031-MY3,黃俊瑩(Huang, Chun-Yin),科技部,探討葡萄糖代謝影響口腔癌增生與轉移的分子機制,$1010000,2015.8.1 ~ 2016.7.31
5﹒ 整合型項下子計畫(主持人),CMU104-S-04,黃俊瑩(Huang, Chun-Yin),本校(含附醫),轉錄因子HBP1調節缺氧性口腔癌細胞侵襲的分子機制探討,$250000,2015.8.1 ~ 2016.7.31
6﹒ 個別型,CMU103-S-29,黃俊瑩(Huang, Chun-Yin),本校(含附醫),榭皮素調節醣解代謝作用影響口腔癌侵襲轉移之機制探討,$210000,2014.11.4 ~ 2015.7.31
7﹒ 個別型,MOST 103-2320-B-039 -031-MY3,黃俊瑩(Huang, Chun-Yin),科技部,探討葡萄糖代謝影響口腔癌增生與轉移的分子機制,$1111000,2014.8.1 ~ 2015.7.31
8﹒ 個別型,NSC 102-2320-B-039-036,黃俊瑩(Huang, Chun-Yin),科技部,轉錄因子HMG box-containing protein 1 (HBP1) 調節脂肪細胞分化之機制研究,$851000,2013.8.1 ~ 2014.7.31
9﹒ 個別型,CMU100-TC-21,黃俊瑩(Huang, Chun-Yin),本校(含附醫),N-acetylcysteine(NAC)抑制上皮生長因子受體活化型口腔癌的分子機制探討,$200000,2012.3.1 ~ 2012.7.31
10﹒ 個別型,NSC 98-2320-B-039-021-MY3,黃俊瑩(Huang, Chun-Yin),科技部,檞皮素 (QUERCETIN) 抑制口腔癌之功效及機制研究,$865000,2011.8.1 ~ 2012.7.31
11﹒ 個別型,NSC 98-2320-B-039-021-MY3,黃俊瑩(Huang, Chun-Yin),科技部,檞皮素 (QUERCETIN) 抑制口腔癌之功效及機制研究,$800000,2010.8.1 ~ 2011.7.31
12﹒ 個別型,NSC 98-2320-B-039-021-MY3,黃俊瑩(Huang, Chun-Yin),科技部,檞皮素 (QUERCETIN) 抑制口腔癌之功效及機制研究,$750000,2009.8.1 ~ 2010.7.31
13﹒ 學生參與計畫,NSC 98-2815-C-039-021-B,黃俊瑩(Huang, Chun-Yin),科技部,NAC抑制口腔癌細胞生長之機制探討,$47000,2009.7.1 ~ 2010.2.28
14﹒ 個別型,CMU97-303,黃俊瑩(Huang, Chun-Yin),本校(含附醫),槲皮素調控轉錄因子HBP1抑制口腔癌之機制探討,$400000,2009.4.1 ~ 2010.3.31
15﹒ 個別型,NSC 96-2321-B-039-006-MY2,黃俊瑩(Huang, Chun-Yin),科技部,轉錄因子HBP1經由REACTIVE OXYGEN SPECIES(ROS)的生成調控而達到對口腔癌中生長因子的訊息傳遞之抑制,$600000,2008.12.1 ~ 2009.7.31
16﹒ 整合型項下子計畫(主持人),CMU97-108,黃俊瑩(Huang, Chun-Yin),本校(含附醫),發炎相關反應在口腔癌發生過程中的重要性--子計畫六:HBP1對口腔癌細胞上皮成長因子受器EGFR-Β-CATENIN的訊息傳遞之抑制機制(2/3),$550000,2008.8.1 ~ 2009.7.31
17﹒ 個別型,NSC 96-2321-B-039-006-MY2,黃俊瑩(Huang, Chun-Yin),科技部,轉錄因子HBP1經由REACTIVE OXYGEN SPECIES(ROS)的生成調控而達到對口腔癌中生長因子的訊息傳遞之抑制,$400000,2007.12.1 ~ 2008.7.31
18﹒ 個別型,CMU95-311,黃俊瑩(Huang, Chun-Yin),本校(含附醫),HBP1對口腔癌細胞上皮成長因子受器 EGFR-β-Catenin的訊息傳遞之抑制,$550000,2007.6.1 ~ 2008.5.31
19﹒ 個別型,CMU95-206,黃俊瑩(Huang, Chun-Yin),本校(含附醫),HBP1抑制乳癌細胞上皮成長因子受體的訊息傳遞,$500000,2006.8.1 ~ 2007.8.31