學術研究成果/Publication
基本資料/Profiles
姓名/Name: 黃俊發 性別/Gender:
英文姓名/
English Name:
英文縮寫/
Abbreviation:
C.F.H.
任職單位/
Affiliation:
1.中醫學院中醫學系學士班中醫方藥學科(教授) / School of Chinese Medicine- Chinese Herbal Medicine (Professor)
Email: cfhuang@mail.cmu.edu.tw
研究專長/Fields of Specialty
1﹒ 毒理學
2﹒ 中藥毒理學
3﹒ 中藥藥理學
4﹒ 環境污染物及重金屬毒理學
5﹒ 糖尿病致病機轉
6﹒ 細胞分子生物學
 
期刊論文/Journal Paper
(作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄)
SCI論文 游俊豪(Jiun-Hao Yu)*、黃俊發、王德皓(Te-Hao Wang)、洪東榮(Dong-Zong Hung)*、穆函蔚(Han-Wei Mu)、潘麒(Chi-Keng Pan),Oxidative Storm in a Patient With Acute Rotenone-Containing Plant Poisoning,AMERICAN JOURNAL OF EMERGENCY MEDICINE,2020 Jun,38(6):1296e1-1296e3
SCI論文 (Cheng-Chin Huang)、(Chun-Ying Kuo)、(Ching-Yao Yang)、(Jui-Ming Liu)、(Ren-Jun Hsu)、(Kuan-I Lee)、(Chin-Chuan Su)、吳錦景(Chin-Ching Wu)、林靖婷(Ching-Ting Lin)、劉興華(Shibg-Hwa Liu)、黃俊發*,Cadmium exposure induces pancreatic β-cell death via a Ca2+-triggered JNK/CHOP-related apoptotic signaling pathway,TOXICOLOGY,2019 Sep,425():152252
SCI論文 (Tien-Huang Lin)、(Yeh Chen)、(Jong-Tar Kuo)、(Yi-Chyi Lai)、(Chien-Chen Wu)、黃俊發、林靖婷(Ching-Ting Lin)*,Phosphorylated OmpR is Required for Type 3 Fimbriae Expression in Klebsiella pneumoniae Under Hypertonic Conditions,Frontiers in Microbiology,2018 Oct,9(2405):1-13
SCI論文 黃俊發(Huang, Chun-Fa)、(Ching-Yao Yang)、(Jing-Ren Tsai)、吳鎮天(Wu, Cheng-Tien)、劉興華(Shibg-Hwa Liu)*、(Kuo-Cheng Lan)*,Low-dose tributyltin exposure induces an oxidative stresstriggered JNK-related pancreatic β-cell apoptosis and a reversible hypoinsulinemic hyperglycemia in mice,Scientific Reports,2018 Apr,8(1):5734-5745
SCI論文 吳鎮天(Wu, Cheng-Tien)、(Chiu, CY)、黃俊發(Huang, Chun-Fa)、劉興華(Shibg-Hwa Liu)*,Genotoxicity and 28-day oral toxicity studies of a functional food mixture containing maltodextrin, white kidney bean extract, mulberry leaf extract, and niacin-bound chromium complex,REGULATORY TOXICOLOGY AND PHARMACOLOGY,2018 Feb,92():
SCI論文 (Hsu RJ)、(Lin CY)、(Chang FW)、黃俊發(Huang, Chun-Fa)、(Chuang HC)、(Liu JM)*,The association between scabies and myasthenia gravis: A nationwide population-based cohort study,JOURNAL OF CLINICAL NEUROSCIENCE,2017 Nov,45():115-120
SCI論文 林殿璜(Tien-Huang Lin)、曾政尹(Cheng-Yin Tseng)、賴怡琪(Yi-Chyi Lai)、吳健誠(Chien-Chen Wu)、黃俊發(Huang, Chun-Fa)、林靖婷(Lin, Ching-Ting)*,IscR Regulation of Type 3 Fimbriae Expression in Klebsiella pneumoniae CG43,Frontiers in Microbiology,2017 Oct,8(1984):1-12
SCI論文 (Jui-Ming Liu)、(Ren-Jun Hsu)、(Fung-Wei Chang)、(Feng-Hsiang Chiu)、(Chia-Lun Yeh)、黃俊發(Huang, Chun-Fa)、(Shu-Ting Chang)、(Hung-Chang Lee)、(Hsin Chi)、(Chien-Yu Lin)*,Increased risk of pernicious anemia following scabies: a nationwide population-based matched-cohort study,Therapeutics and Clinical Risk Management,2017 Sep,13():1205-1211
SCI論文 林千裕(Chien-Yu Lin)、Fung-Wei Cha(Fung-Wei Chan)、楊境中(Jing-Jung Yang)、張俊鴻(Chun-Hung Chang)、葉家綸(Chia-Lun Yeh)、雷偉德(Wei-Te Lei)、黃俊發(Huang, Chun-Fa)、柳瑞明(Jui-Ming Liu)、許仁駿(Ren-Jun Hsu)*,Increased risk of bipolar disorder in patients with scabies: A nationwide population-based matched-cohort study,PSYCHIATRY RESEARCH,2017 Jul,8(257):14-20
SCI論文 (Jui-Ming Liu)、(Ren-Jun Hsu)、(Fung-Wei Chang)、(Chia-Lun Yeh)、黃俊發(Chun-Fa Huang)、(Shu-Ting Chang)、(Nan-Chang Chiu)、(Hung-Yang Chang)、(Hsin Chi)、(Chien-Yu Lin)*,Increase the risk of intellectual disability in children with scabies: A nationwide population-based cohort study,MEDICINE,2017 Jun,96(23):e7108-e7114
SCI論文 (Kuan-I Lee)、(Chin-Chuan Su)、(Ching-Yao Yang)、洪東榮(Hung, Dong-Zong)、林靖婷(Ching-Ting Lin)、(Tien-Hui Lu)、劉興華(Shibg-Hwa Liu)*、黃俊發(Chun-Fa Huang)*,Etoposide induces pancreatic beta-cells cytotoxicity via the JNK/ERK/GSK-3 signaling-mediated mitochondria-dependent apoptosis pathway,TOXICOLOGY IN VITRO,2016 Oct,36():142-152
SCI論文 林靖婷(Ching-Ting Lin)*、(Tien-Huang Lin)、(Chien-Chen Wu)、萬磊(Lei Wan)、黃俊發(Chun-Fa Huang)、(Hwei-Ling Peng)*,CRP-Cyclic AMP Regulates the Expression of Type 3 Fimbriae via Cyclic di-GMP in Klebsiella pneumoniae,PLoS One,2016 Sep,11(9):e0162884
Other論文 洪東榮(Hung, Dong-Zong)、(Hon-Pin Lee)、黃俊發(Chun-Fa Huang)*,The Last Dinner: Fatality of 2-Chloroethanol Intoxication,Journal of Clinical Toxicology,2016 Aug,6(4):314-316
SCI論文 (Tsung-Yuan Yang)、(Cheng-Chieh Yen)、(Kuan-I Lee)、(Chin-Chuan Su)、(Ching-Yao Yang)、吳錦景(Chin-Ching Wu)、(Shang-Shu Hsieh)*、(Kwo-Chang Ueng)*、黃俊發(Chun-Fa Huang)*,Molybdenum induces pancreatic beta-cell dysfunction and apoptosis via interdependent of JNK and AMPK activation-regulated mitochondria-dependent and ER stress-triggered pathways,TOXICOLOGY AND APPLIED PHARMACOLOGY,2016 Mar,294():54-64
SCI論文 黃俊發(Chun-Fa Huang)、(Yang CY)、(Chan DC)、(Wang CC)、(Huang KH)、吳錦景(Chin-Ching Wu)、(Tsai KS)、(Yang RS)、(Shibg-Hwa Liu)*,Arsenic Exposure and Glucose Intolerance/Insulin Resistance in Estrogen-Deficient Female Mice,ENVIRONMENTAL HEALTH PERSPECTIVES,2015 Nov,123(11):1138-1144
SCI論文 (Chin-Chuan Su)、(Shing-Hwa Liu)、(Kuan-I Lee)、(Kou-Tong Huang)、(Tien-Hui Lu)、(Kai-Min Fang)、吳錦景(Chin-Ching Wu)、(Cheng-Chieh Yen)、賴志河(Chih-Ho Lai)、蘇奕彰(Yi-chang, Su)、黃俊發(Chun-Fa Huang)*,Cantharidin induces apoptosis through the calcium/PKC-regulated endoplasmic reticulum stress pathway in human bladder cancer cells,AMERICAN JOURNAL OF CHINESE MEDICINE,2015 May,43(3):581-600
SCI論文 洪東榮(Hung, Dong-Zong)*、林靖華、毛彥喬、黃俊發(Chun-Fa Huang)、廖明一,Rapid diagnosis of Naja atra snakebites,CLINICAL TOXICOLOGY,2014 Mar,52(3):187-191
SCI論文 (Chia-Fang Tsai)、(Yu-Wen Hsu)、(Hung-Chih Ting)、黃俊發(Chun-Fa Huang)、(Cheng-Chieh Yen)*,The in vivo antioxidant and antifibrotic properties of green tea (Camellia sinensis,Theaceae),FOOD CHEMISTRY,2013 Feb,136(3-4):1337-1344
SCI論文 (Feng-Lin Hsu)、黃俊發(Chun-Fa Huang)、陳雅雯(Ya-Wen Chen)、(Yuan-Peng Yen)、(Cheng-Tien Wu)、(Biing-Jiun Uang)、(Rong-Sen Yang)、(Shing-Hwa Liu)*,Antidiabetic Effects of Pterosin A, a Small-Molecular-Weight Natural Product, on Diabetic Mouse Models,DIABETES,2013 Feb,62(2):628-638
SCI論文 (Kai-Chih Chang)、(Ching-Cheng Hsu)、(Shing-Hwa Liu)、(Chin-Chuan Su)、(Cheng-Chieh Yen)、(Ming-Jye Lee)、陳國樑(Chen, Kuo-Liang)、何宗融(Tsung-Jung Ho)、洪東榮(Hung, Dong-Zong)、吳錦景(Chin-Ching Wu)、(Tien-Hui Lu)、蘇奕彰(Yi-chang, Su)、陳雅雯(Ya-Wen Chen)*、黃俊發(Chun-Fa Huang)*,Cadmium induces apoptosis in pancreatic -cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation,PLoS One,2013 Feb,8(2):e54374-e54385
SCI論文 陳俊宏(Chun-Hung Chen)、(Sz-Jie Chen)、(Chin-Chuan Su)、(Cheng-Chieh Yen)、曾拓榮(Tseng, To-Jung)、靳子蓉(Tzyy-Rong Jinn)、(Feng-Cheng Tang)、陳國樑(Chen, Kuo-Liang)、蘇奕彰(Yi-chang, Su)、(kuan-I Lee)、洪東榮(Hung, Dong-Zong)*、黃俊發(Chun-Fa Huang)*,Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals,TOXICOLOGY,2013 Jan,303(1):72-82
SCI論文 黃俊發(Chun-Fa Huang)、(Shing-Hwa Liu)、(Shoei-Yn Lin-Shiau)*,Pyrrolidine dithiocarbamate augments Hg2+-mediated induction of macrophage cell death via oxidative stress-induced apoptosis and necrosis signaling pathways,TOXICOLOGY LETTERS,2012 Oct,214(1):33-45
SCI論文 陳國樑(Chen, Kuo-Liang)、(Shing-Hwa Liu)、(Chin-Chuan Su)、(Cheng-Chieh Yen)、(Ching-Yao Yang)、(kuan-I Lee)、(Feng-Cheng Tang)、陳雅雯(Ya-Wen Chen)、(Tien-Hui Lu)、蘇奕彰(Yi-chang, Su)、黃俊發(Chun-Fa Huang)*,Mercuric compounds induce pancreatic islets dysfunction and apoptosis in vivo,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2012 Oct,13(10):12349-12366
SCI論文 黃俊發(Chun-Fa Huang)、(Chuan-Jen Hsu)、(Shing-Hwa Liu)、(Shoei-Yn Lin-Shiau)*,Exposure to low-dose of cinnabar (a naturally occurring mercuric sulfide (HgS)) caused neurotoxicological effects in offspring mice,JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY,2012 Aug,2012(2012):254582-254593
SCI論文 (Yuan-Peng Yen)、(Keh-Sung Tsai)、陳雅雯(Ya-Wen Chen)、黃俊發(Chun-Fa Huang)、(Rong-Sen Yang)*、(Shing-Hwa Liu)*,Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway,ARCHIVES OF TOXICOLOGY,2012 Jun,86(6):923-933
SCI論文 Hsieh SK、曾志正、Wu TY、Chen YJ、楊維宏(Wei-Hung Yang)、黃俊發(Chun-Fa Huang)、(Hsieh FC)、靳子蓉(Tzyy-Rong Jinn)*,Functional Expression and Characterization of Dipeptidyl peptidase IV from the Black-Bellied Hornet Vespa basalis in Sf21 Insect Cells.,BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,2011 Dec,75(12):2371-2375
SCI論文 (Yu-Wen Hsu)、(Chia-Fang Tsai)、(Wen-Kang Chen)、黃俊發(Chun-Fa Huang)、(Cheng-Chieh Yen)*,A subacute toxicity evaluation of green tea (Camellia sinensis) extract in mice,FOOD AND CHEMICAL TOXICOLOGY,2011 Oct,49(10):2624-2630
SCI論文 黃俊發(Chun-Fa Huang)、陳雅雯(Ya-Wen Chen)、楊卿堯(Ching Yao Yang)、(Keh Sung Tsai)、楊榮森(Rong Sen Yang)*、劉興華(Shing Hwa Liu)*,Arsenic and diabetes: Current perspectives,KAOHSIUNG JOURNAL OF MEDICAL SCIENCES,2011 Sep,27(9):402-410
SCI論文 黃俊發(Chun-Fa Huang)、楊榮森(Rong-Sen Yang)、劉興華(Shing-Hwa Liu)、(Po-Chow Hsieh)、蕭水銀(Shoei-Yn Lin-Shiau)*,Evidence Based for Improved Neuropharmacological Efficacy and Decreased Neurotoxicity in Mice with Traditional Processing of Rhizoma Arisaematis,AMERICAN JOURNAL OF CHINESE MEDICINE,2011 Sep,39(5):981-998
SCI論文 吳錫金(Wu,Hsi-Chin)、楊卿堯(Ching-Yao Yang)、洪東榮(Hung, Dong-Zong)、(Chin-Chuan Su)、陳國樑(Chen, Kuo-Liang)、(Cheng-Chieh Yen)、何宗融(Tsung-Jung Ho)、蘇奕彰(Yi-chang, Su)、黃俊發(Chun-Fa Huang)、陳俊宏(Chun-Hung Chen)、(Ling-Mei Tsai)、陳雅雯(Ya-Wen Chen)*,Nickel(II) induced JNK activation-regulated mitochondria-dependent apoptotic pathway leading to cultured rat pancreatic ß-cell death,TOXICOLOGY,2011 Aug,289(2011):103-111
SCI論文 呂恬慧(Tien-Hui Lu)、謝尚諭(Shan-Yu Hsieh)、巖正傑(Cheng-Chien Yen)、吳錫金(Wu,Hsi-Chin)、陳國樑(Chen, Kuo-Liang)、洪東榮(Hung, Dong-Zong)、陳俊宏(Chun-Hung Chen)、吳錦景(Chin-Ching Wu)、蘇奕彰(Yi-chang, Su)、陳雅雯(Ya-Wen Chen)、劉興華(Shing-Hwa Liu)*、黃俊發(Chun-Fa Huang)*,Involvement of oxidative stress-mediated ERK1/2 and p38 activation regulated mitochondria-dependent apoptotic signals in methylmercury-induced neuronal cell injury,TOXICOLOGY LETTERS,2011 Jul,204(1):71-80
SCI論文 巖正傑(Cheng-Chien Yen)、何宗融(Tsung-Jung Ho)、吳錦景(Chin-Ching Wu)、張春芳(Chun-Fang Chang)、蘇金泉(Chin-Chuan Su)、陳雅雯(Ya-Wen Chen)、靳子蓉(Tzyy-Rong Jinn)、呂恬慧(Tien-Hui Lu)、鄭博文(Po-Wen Cheng)、蘇奕彰(Yi-chang, Su)、劉興華(Shing-Hwa Liu)*、黃俊發(Chun-Fa Huang)*,Inorganic arsenic causes cell apoptosis in mouse cerebrum through an oxidative stress-regulated signaling pathway,ARCHIVES OF TOXICOLOGY,2011 Jun,85(6):565-575
SCI論文 黃俊發(Chun-Fa Huang)、劉興華(Shing-Hwa Liu)、許權振(Chuan-Jen Hsu)、林蕭水銀(Shoei-Yn Lin-Shiau)*,Neurotoxicological effects of low-dose methylmercury and mercuric chloride in developing offspring mice,TOXICOLOGY LETTERS,2011 Mar,201(3):196-204
SCI論文 呂恬慧(Tien-Hui Lu)、(Chin-Chuan Su)、陳雅雯(Ya-Wen Chen)、楊卿堯(Ching-Yao Yang)、吳錦景(Chin-Ching Wu)、洪東榮(Hung, Dong-Zong)、陳俊宏(Chun-Hung Chen)、(Po-Wen Cheng)、劉興華(Shing-Hwa Liu)、黃俊發(Chun-Fa Huang)*,Arsenic induces pancreatic β-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling pathways,TOXICOLOGY LETTERS,2011 Feb,201(1):15-26
SCI論文 黃俊發(Chun-Fa Huang)、陳雅雯(Ya-Wen Chen)、楊卿堯(Ching-Yao Yang)、林慧怡(Lin, Hui-Yi)、魏宗德(Tzong-Der Way)、(Wenchang Chiang)、劉興華(Shing-Hwa Liu)*,Extract of Lotus Leaf (Nelumbo nucifera) and Its Active Constituent Catechin with Insulin Secretagogue Activity,JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2011 Feb,59(4):1087-1094
SCI論文 (Yen YP)、(Tsai KS)、陳雅雯(Ya-Wen Chen)、黃俊發(Chun-Fa Huang)、(Yang RS)*、(Liu SH)*,Arsenic Inhibits Myogenic Differentiation and Muscle Regeneration,ENVIRONMENTAL HEALTH PERSPECTIVES,2010 Jul,118(7):949-956
SCI論文 陳雅雯(Ya-Wen Chen)、黃俊發(Chun-Fa Huang)、楊卿堯(Yang CY)、巖正傑(Yen CC)、蔡克嵩(Tsai KS)*、劉興華(Liu SH)*,Inorganic mercury causes pancreatic β-cell death via the oxidative stress-induced apoptotic and necrotic pathways,TOXICOLOGY AND APPLIED PHARMACOLOGY,2010 Mar,243():323-331
SCI論文 湯智昕(Tang Chih-Hsin)*、(Yung-Cheng Chiu)、黃俊發(Chun-Fa Huang)、陳雅雯(Ya-Wen Chen)、(Po-Chun Chen),Arsenic induces cell apoptosis in cultured osteoblasts through endoplasmic reticulum stress,TOXICOLOGY AND APPLIED PHARMACOLOGY,2009 Dec,241(2):173-181
Other論文 陳雅雯(Ya-Wen Chen)、(Ching Yao Yang)、黃俊發(Chun-Fa Huang)、洪東榮(Hung, Dong-Zong)、梁育民、(Shing Hwa Liu)*,Heavy metals and islet function and diabetes development,Islets,2009 Nov,1(3):1-8
SCI論文 楊榮森(Rong Sen Yang)、曾惠萍(Huei Ping Tzeng)、何豐名(Feng Ming Ho)、莊佳琪(Chia Chi Chuang)、陳柏霖(Bo Lin Chen)、黃俊發(Chun-Fa Huang)、陳雅雯(Ya-Wen Chen)、(Ruei Ming Chen)、劉興華(Shing Hwa Liu)*,Titanium implants alter endothelial function and vasoconstriction via a protein kinase C-regulated pathway.,Acta Biomaterialia,2009 Oct,5():3258-3264
SCI論文 陳雅雯(Ya-Wen Chen)、呂彥禮(Yann Lii Leu)、楊卿堯(Ching Yao Yang)、黃俊發(Chun-Fa Huang)、(Guan Hong Lin)、蔡克嵩(Keh Sung Tsai)、楊榮森(Rong Sen Yang)*、劉興華(Shing Hwa Liu)*,Extract isolated from Angelica hirsutiflora with insulin secretagogue activity,JOURNAL OF ETHNOPHARMACOLOGY,2009 Jun,123(2):208-212
SCI論文 黃俊發(Chun-Fa Huang)、許權振(Chuan-Jen Hsu)、劉興華(Shing-Hwa Liu)、蕭水銀(Shoei-Yn Lin-Shiau)*,Ototoxicity induced by cinnabar (a naturally occurring HgS) in mice through oxidative stress and down-regulated Na+/K+-ATPase activities,NEUROTOXICOLOGY,2008 May,29(3):386-396
SCI論文 黃俊發(Chun-Fa Huang)、許權振(Chuan-Jen Hsu)、劉興華(Shing-Hwa Liu)、蕭水銀(Shoei-Yn Lin-Shiau)*,Neurotoxicological mechanism of methylmercury induced by low-dose and long-term exposure in mice: oxidative stress and down-regulated Na+/K+-ATPase involved,TOXICOLOGY LETTERS,2008 Feb,176():188-197
SCI論文 黃俊發(Chun-Fa Huang)、劉興華(Shing-Hwa Liu)、蕭水銀(Shoei-Yn Lin-Shiau)*,Neurotoxicological effects of cinnabar (a Chinese mineral medicine, HgS) in mice,TOXICOLOGY AND APPLIED PHARMACOLOGY,2007 Dec,224():192-201
SCI論文 嚴正傑(Cheng-Chieh Yen)、呂峰洲(Fung-Jou Lu)、黃俊發(Chun-Fa Huang)、陳文貴(Wen-Kang Chen)、劉興華(Shing-Hwa Liu)、蕭水銀(Shoei-Yn Lin-Shiau),The diabetogenic effects of the combination of humic acid and arsenic: In vitro and in vivo studies,TOXICOLOGY LETTERS,2007 Sep,172():91-105
EI論文 嚴正傑(Cheng-Chieh Yen)、黃俊發(Chun-Fa Huang)、李維俊(W-J Lee)、(M-J Hsu)、劉興華(Shing-Hwa Liu)、蕭水銀(Shoei-Yn Lin-Shiau)*,Studies on mercurial sulfide, a component of cinnabar, a Chinese herbal medicine, on celluar functions in mouse lung and fibroblasts. Toxicological and Environmental Chemistry,Toxicological and Environmental Chemistry,2007 Sep,90(1):181-201
SCI論文 陳雅雯(Ya-Wen Chen)、黃俊發(Chun-Fa Huang)、蔡克嵩(Keh-Sung Tsai)、楊榮森(Rong-Sen Yang)、巖正傑(Cheng-Chieh Yen)、楊卿堯(Ching-Yao Ya)、林蕭水銀(Shoei-Yn Lin-Shiau)、劉興華(Shing-Hwa Liu)*,Methylmercury induces pancreatic beta-cell apoptosis and dysfunction.,CHEMICAL RESEARCH IN TOXICOLOGY,2006 Aug,19():1080-1085
SCI論文 陳雅雯(Ya-Wen Chen)、黃俊發(Chun-Fa Huang)、蔡克嵩(Keh-Sung Tsai)、楊榮森(Rong-Sen Yang)、巖正傑(Cheng-Chieh Yen)、楊卿堯(Ching-Yao Ya)、林蕭水銀(Shoei-Yn Lin-Shiau)、劉興華(Shing-Hwa Liu)*,The Role of Phosphoinositide 3-Kinase/Akt Signaling in Low-Dose Mercury-Induced Mouse Pancreatic β-Cell Dysfunction In Vitro and In Vivo.,DIABETES,2006 May,55():1614-1624
 
研討會論文/Conference Papers
(發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目)
1﹒ Bisphenol A and 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene induces neuronal cell apoptosis via Akt/endoplasmic reticulum stress-regulated signaling pathway,The 53nd Annual Meeting of the Society of Toxicology,Phoenix, Arizona, U.S.A.,2014.3.23 ~ 2014.3.27,
2﹒ Nelumbo nucifera leaf extract induced pancreatic cancer apoptosis via JNK/ERK activation-regulated mitochondria-dependent and ER stress-triggered signaling pathways,The 53nd Annual Meeting of the Society of Toxicology,Phoenix, Arizona, U.S.A.,2014.3.23 ~ 2014.3.27,
3﹒ Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways,The 53nd Annual Meeting of the Society of Toxicology,Phoenix, Arizona, U.S.A.,2014.3.23 ~ 2014.3.27,
4﹒ Methylmercury induces apoptosis in neuronal cells through ROS-mediated endoplasmic reticulum stress-regulated signaling pathway,The 53nd Annual Meeting of the Society of Toxicology,Phoenix, Arizona, U.S.A.,2014.3.23 ~ 2014.3.27,
5﹒ Etoposide-induced mitochondria-dependent apoptosis through c-jun N-terminal kinases, extracellular signal-regulated kinases, and glycogen synthesis kinase 3 alpha/beta pathway in pancreatic beta-cells.,The 52nd Annual Meeting of the Society of Toxicology,San Antonio, Texas, USA,2013.3.10 ~ 2013.3.14,
6﹒ Berberine induces human tongue squamous carcinoma cell apoptosis through PI3K-regulated ER stress pathway.,The 52nd Annual Meeting of the Society of Toxicology,San Antonio, Texas, USA,2013.3.10 ~ 2013.3.14,
7﹒ Silica nanoparticles induce acute pulmonary toxicity in mice.,The 52nd Annual Meeting of the Society of Toxicology,San Antonio, Texas, USA,2013.3.10 ~ 2013.3.14,
8﹒ Paraquat causes hepatocytes death via oxidative stress-induced JNK/ERK activation regulated mitochondria-dependent apoptosis pathway.,The 52nd Annual Meeting of the Society of Toxicology,San Antonio, Texas, USA,2013.3.10 ~ 2013.3.14,
9﹒ Methylmercury-induced mouse sertoli cells apoptosis via regulation of mitochondrial-dependent pathway,The 6th International Congress of Asian Society of Toxicology (第六屆亞洲毒理學會國際研討會),Sendai, Japan,2012.7.17 ~ 2012.7.20,
10﹒ Cadmium-induced oxidative stress damage causes neuron cells apoptosis through JNK/mitochondria-dependent/endoplasmic reticulum stress pathways,The 51th Annual Meeting of the Society of Toxicology,美國,舊金山,2012.3.11 ~ 2012.3.15,
11﹒ Pyrrolidine dithiocarbamate augments Hg2+ in inducing macrophage cell death through oxidative stress-induced apoptosis and necrosis signaling pathways,The 51th Annual Meeting of the Society of Toxicology,美國,舊金山,2012.3.11 ~ 2012.3.15,
12﹒ Silica nanoparticles induces cell death in lung epithelial cells through mitochondria and endoplasmic reticulum pathways,The 51th Annual Meeting of the Society of Toxicology,美國,舊金山,2012.3.11 ~ 2012.3.15,
13﹒ Chloroacetic acid induced cell apoptosis through ROS/endoplasmic reticulum stress pathway in neuronal cell,The 51th Annual Meeting of the Society of Toxicology,美國,舊金山,2012.3.11 ~ 2012.3.15,
14﹒ Involvement of oxidative stress-induced ERK/JNK activation in the Cu2+/pyrrolidine dithiocarbamate complex-triggered mitochondria-regulated apoptosis in pancreatic -cells,The 51th Annual Meeting of the Society of Toxicology,美國,舊金山,2012.3.11 ~ 2012.3.15,
15﹒ Extracts from Lotus Leaf (Nelumbo nucifera) induced human pancreatic cancer cell apoptosis,2011傳統中醫藥及中草藥醫學研討會,中國醫藥大學,2011.9.10 ~ 2011.9.10,
16﹒ The extracts from Lotus Leaf (Nelumbo nucifera) prevent LPS-induced inflammatory in RAW 264.7 marcrophage through MAPK and NF-B mediated signaling pathways,2011傳統中醫藥及中草藥醫學研討會,中國醫藥大學,2011.9.10 ~ 2011.9.10,
17﹒ ,2011EAPCCT 2011-XXXI International congress,歐洲 克羅埃西亞,2011.5.23 ~ 2011.5.27,
18﹒ Inorganic arsenic causes apoptosis in mouse cerebrum through an oxidative stress-induced MAPKs and ER stress pathway,The 50th Annual Meeting of the Society of Toxicology,美國,華盛頓,2011.3.6 ~ 2011.3.10,
19﹒ Intraventricular conduction delay after Glyphosate-surfactant herbicides intoxication,The 50th Annual Meeting of the Society of Toxicology,美國,華盛頓,2011.3.6 ~ 2011.3.10,
20﹒ THE MECHANISMS OF PARAQUAT-INDUCED LUNG TOXICITY IN VIVO AND IN VITRO,The 50th Annual Meeting of the Society of Toxicology,美國,華盛頓,2011.3.6 ~ 2011.3.10,
21﹒ Oxidative stress-mediated ERK1/2, p38 and mitochondrial-dependent signaling pathways involve in Methylmercury induces the neuronal cell apoptosis,The 50th Annual Meeting of the Society of Toxicology,美國,華盛頓,2011.3.6 ~ 2011.3.10,
22﹒ Methylmercury induced pancreatic β-cell apoptosis through endoplasmic reticulum stress,The 50th Annual Meeting of the Society of Toxicology,美國,華盛頓,2011.3.6 ~ 2011.3.10,
23﹒ Nickel(II) chloride causes pancreatic islet beta-cell death via a JNK-regulated mitochondrial apoptotic pathway,The 50th Annual Meeting of the Society of Toxicology,美國,華盛頓,2011.3.6 ~ 2011.3.10,
24﹒ An anti-hyperglycemic effect of extract isolated from seed of Benincasa hispida extract (SBE) in high fat diet-induced type II diabetic mice,第26屆生物醫學聯合學術年會,國防醫學大學,2011.3.19 ~ 2011.3.20,
25﹒ The role of oxidative stress damage in paraquat-induced hepatotoxicity in vitro,第26屆生物醫學聯合學術年年,國防醫學大學,2011.3.19 ~ 2011.3.20,
26﹒ THE EFFECTS OF TESTOSTERONE ON THE SECRETION OF INSULIN,第10屆亞洲泌尿科醫學會議(10th Asian Congress of Urology of the Urological Association of Asia),台北國際會議中心,2010.8.27 ~ 2010.8.31,
27﹒ 2-Chloroacetadehyde and 2-chloroacetic acid induced neuronal cell death: oxidative stress and down-regulated mitochondria dependent apoptosis pathway,International Conference on Emergency Medicine (ICEM) 2010,Suntec Singapore International Convention & Exhibition Center,2010.6.9 ~ 2010.6.12,
28﹒ Polyoxyethylene alkylphenol ether (nonionic surfactant)-induced lung tissue dysfunction and lung epithelial cell death,International Conference on Emergency Medicine (ICEM) 2010,Suntec Singapore International Convention & Exhibition Center,2010.6.9 ~ 2010.6.12,
29﹒ Cadmium-induced pancreatic islet β-cells dysfunction and cell death: through ROS mediated MAPK-mitochondrial dependent apoptosis pathway,The 49th Annual Meeting of the Society of Toxicology,Salt Lake City, Utah, USA.,2010.3.7 ~ 2010.3.11,
30﹒ Mercury Chloride-Induces Pancreatic -cell Death: Involve of Apoptosis and Necrosis.,The 49th Annual Meeting of the Society of Toxicology,Salt Lake City, Utah, USA.,2010.3.7 ~ 2010.3.11,
31﹒ Studies of the role of Mitogen-activated protein kinase regulated apoptosis signaling pathways in cadmium-induced pancreatic β-cells death,第 25 屆 生物醫學聯合學術年會,國防醫學院,2010.3.27 ~ 2010.3.28,
32﹒ Cadmium induces cell death in neuro-2a cells through reactive oxygen species-regulated mitochondrial and endoplasmic reticulum stress pathways,第 25 屆 生物醫學聯合學術年會,國防醫學院,2010.3.27 ~ 2010.3.28,
33﹒ Studies of mechanism of cadmium-induced pancreatic islet β-cell dysfunction and cell death.,教育部獎勵大學教學卓越計畫97年度中國醫藥大學P3-4研究學群之推廣-2009研究學習群校級研究成果發表會,中國醫藥大學,2009.6.5 ~ 2009.6.5,
34﹒ he role of oxidative stress in methylmercury induced lung epithelial cell damage and lung damage,教育部獎勵大學教學卓越計畫97年度中國醫藥大學P3-4研究學群之推廣-2009研究學習群校級研究成果發表會,中國醫藥大學,2009.6.5 ~ 2009.6.5,
35﹒ Cadmium Alters the Function and Survival of Pancreatic β-cells,第 24 屆 生物醫學聯合學術年會,國防醫學院,2009.3.21 ~ 2009.3.22,
36﹒ Methylmercury Induces Cell Death in Alveolar Type II Epithelial Cells Through Mitochondria and Endoplasmic Reticulum Pathways,第 24 屆 生物醫學聯合學術年會,國防醫學院,2009.3.21 ~ 2009.3.22,
37﹒ Extract Isolated From Semen Benincasae With Insulin Secretagogue Activity,第23屆生物醫學聯合學術年會,國防醫學院,2008.3.29 ~ 2008.3.30,
38﹒ Effects Of Tributyltin On The Pancreatic beta-Cell Growth And Function,第23屆生物醫學聯合學術年會,國防醫學院,2008.3.29 ~ 2008.3.30,
39﹒ Mercury-Induced Pancreatic –Cell Death: Involvement of Apoptosis and Necrosis,Eighth Annual Rachmiel Levine Diabetes and Obesity Symposium,Los Angeles,2008.1.13 ~ 2008.1.16,
40﹒ Studies on The Mechanism Of Action Of Oxidative Stress On The Regulation Of Insulin Secretion,第22屆生物醫學聯合學術年會,國防大學國防醫學院,2007.3.17 ~ 2007.3.18,
41﹒ Extract From Angelica Hirsutiflora With Hypoglycemic Activity,第 22 屆 生物醫學聯合學術年會,國防大學國防醫學院,2007.3.17 ~ 2007.3.18,
42﹒ Humic Acid and Arsenic Reduce Insulin Secretion: The Relations with the Pathogenesis of Diabetes Mellitus In Vivo and In Vitro Experimentation,第 21 屆 生物醫學聯合學術年會,國防醫學大學,2006.3.18 ~ 2006.3.19,
43﹒ Cytotoxicity Of Mercurial Compounds In V79 And HL-60 Cells: Roles Of Glutathione And Oxidative Stress,第 20 屆 生物醫學聯合學術年會,國防醫學大學,2005.3.26 ~ 2005.3.27,
44﹒ Effects Of Humic Acid And Arsenic: The Relations With The Pathogenesis of Diabetes Mellitus,第 20 屆 生物醫學聯合學術年會,國防醫學大學,2005.3.26 ~ 2005.3.27,
45﹒ Modulatory effects of mercuric sulfide on behavioral changes of mice induced by methamphetamine,物質濫用研討會,成功大學醫學院,2005.2.26 ~ 2005.2.26,
46﹒ Implication of nitric oxide production in the altered behaviors of mice administered with combined lipopolysaccharide and methamphetamine,第三屆亞洲毒理學研討會,泰國,2004.2.1 ~ 2004.2.6,
47﹒ Studies On The Altered Behaviors And Ototoxicity Found In The Third Generations Of The Cinnabar-Fed Mice,中華民國基礎神經科學學會2003年會員大會暨學術研討會,台大醫院第七講堂,2003.10.18 ~ 2003.10.18,
48﹒ Studies on The Deaths Signaling in The Murine Macrophages Induced by HgS-Meatl Chelator Complexes,第2屆海峽兩岸毒理學研討會,中央研究院,2003.10.22 ~ 2003.10.23,
49﹒ The Death Signaling Pathway of Mercury Sulfide on The Culture Human Umbilical Vein Endothelial Cells,第 18 屆 生物醫學聯合學術年會,台大醫學院,2003.3.22 ~ 2003.3.23,
50﹒ Effects of Mercury Sulfide on Auditory Brainstem Responses and Locomotor Activity of Mice,中華民國基礎神經科學學會二00二年會員大會暨學術研討會,國防醫學院第三十教室,2002.10.5 ~ 2002.10.5,
51﹒ Low Dose Mercury Sulfide Suppressed The Stimulatory Effects Of Methyl-amphetamine On Locomotor Activity Of Mice,第17屆生物醫學年會,國防醫學大學,2002.3.23 ~ 2002.3.24,
 
研究計畫/Research Grant
(研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,研究經費,計畫期間)
1﹒ 個別型,MOST 109-2320-B-039-049-MY3,林靖婷(Ching-Ting Lin),黃俊發,科技部,蛋白質乙醯化及其在克雷白氏肺炎桿菌致病機轉中的角色,$1610000,2020.8.1 ~ 2021.7.31
2﹒ 學生參與計畫,CMU108-SR-57,黃俊發,本校(含附醫),銻金屬(Antimony)誘發胰島beta細胞毒性損傷與分子作用機制之研究-探求ROS於其中所扮演之關鍵角色,$35000,2019.8.1 ~ 2020.2.28
3﹒ 學生參與計畫,108-2813-C-039-084-B,黃俊發,科技部,銻金屬(Antimony)誘發胰島beta細胞毒性損傷與分子作用機制之研究-探求ROS於其中所扮演之關鍵角色,$48000,2019.7.1 ~ 2020.2.28
4﹒ 個別型,MOST 107-2320-B-039-045-,黃俊發,科技部,環境毒性重金屬汙染物質與糖化終產物(AGEs)破壞胰島beta細胞胰島素生合成與分泌作用之毒理作用機制研究: 探討Sirtuins蛋白家族於其中之重要角色,$1080000,2018.8.1 ~ 2019.7.31
5﹒ 個別型,MOST 106-2320-B-039-003-,黃俊發(Huang, Chun-Fa),科技部,鎘金屬破壞胰島素生合成與分泌(胞吐)作用之毒理作用機制研究:探討SNARE 蛋白家族與雌激素受體於其中之重要角色,$1310000,2017.8.1 ~ 2018.10.31
6﹒ 個別型,MOST 105-2320-B-039-026-,黃俊發(Chun-Fa Huang),林慧怡(Lin, Hui-Yi)、蘇奕彰(Yi-chang, Su),科技部,白花蛇舌草及其活性成份應用於預防及治療肥胖、及其所引起高血糖與高血 脂症之新穎性功效探討、及研究其分子作用機制,$950000,2016.8.1 ~ 2017.7.31
7﹒ 個別型,MOST 104-2320-B-039-014,黃俊發(Chun-Fa Huang),劉興華、林慧怡(Lin, Hui-Yi)、蘇奕彰(Yi-chang, Su),科技部,白花蛇舌草及其活性成份應用於預防及治療肥胖、及其所引起高血糖與高血脂症之新穎性功效探討、及研究其分子作用機制,$1000000,2015.8.1 ~ 2016.7.31
8﹒ 個別型,MOST 104-2320-B-039-037,林靖婷(Ching-Ting Lin),黃俊發(Chun-Fa Huang),科技部,環腺苷酸訊號路徑對於克雷白氏肺炎桿菌在致病機轉上的影響,$940000,2015.8.1 ~ 2016.7.31
9﹒ 個別型,MOST 103-2314-B-039-014,黃俊發(Chun-Fa Huang),科技部,鎘金屬影響胰島素生合成及胞吐作用之毒理作用機制研究:探討SNARE 蛋白家族和雌激素受體於其中之重要角色,$1000000,2014.8.1 ~ 2015.7.31
10﹒ 個別型,NSC101-2314-B-039-043-MY2,黃俊發(Chun-Fa Huang),科技部,環境雌激素雙酚A與其活性代謝物對於葡萄糖代謝/恆定之影響及作用機制之探討,$1100000,2013.8.1 ~ 2014.7.31
11﹒ 非研究型計畫 (例如:課程計畫),NSC 102-2918-I-039-006,黃俊發(Chun-Fa Huang),科技部,探討雙酚A與4,4′—(1,1—二甲基—3—亞甲基—1,3—亞丙基)雙苯酚干擾/破壞胰島beta細胞胰島素生合成與分泌功能及其分子作用機制,$313000,2012.10.26 ~ 2013.9.14
12﹒ 個別型,NSC101-2314-B-039-043-MY2,黃俊發(Chun-Fa Huang),科技部,環境雌激素雙酚A與其活性代謝物對於葡萄糖代謝/恆定之影響及作用機制之探討,$1100000,2012.8.1 ~ 2013.7.31
13﹒ 整合型項下子計畫(主持人),NSC 101-2320-B-039-042,黃俊發(Chun-Fa Huang),科技部,鄰苯二甲酸2-乙基己基酯及雙酚A 之非生殖系統之器官毒理學評估,-鄰苯二甲酸2-乙基己基酯及雙酚A對於中樞神經系統之毒理學評估,$1270000,2012.8.1 ~ 2013.7.31
14﹒ 個別型,CCMP101-RD-101,黃俊發(Chun-Fa Huang),蘇奕彰(Yi-chang, Su)、陳雅雯(Ya-Wen Chen)、吳錦景(Chin-Ching Wu),衛福部,以動物模式評估比較硃砂單方及含硃砂之複方中藥對於肝臟和腎臟毒性損傷與安全性研究(2-2),$1000000,2012.1.16 ~ 2012.12.15
15﹒ 個別型,CMU99-N1-07-2,黃俊發(Chun-Fa Huang),本校(含附醫),甲基汞誘發神經退化與細胞損傷作用機制之研究-探討MAPK蛋白活化於其中所扮演的角色,$100000,2011.8.1 ~ 2011.9.30
16﹒ 個別型,NSC 100-2314-B-039-023-,黃俊發(Chun-Fa Huang),劉興華(Shing-Hwa Liu)、陳雅雯(Ya-Wen Chen),科技部,環境荷爾蒙導致胰島細胞胰島素分泌與周邊組織細胞葡萄糖恆定損傷之分子機制及雌激素受體之角色探討,$970000,2011.8.1 ~ 2012.7.31
17﹒ 學生參與計畫,CMU100-SR-22,黃俊發(Chun-Fa Huang),本校(含附醫),環境汙染物-雙酚A引起肺臟上皮細胞損傷及作用機轉之探討,$35000,2011.8.1 ~ 2012.2.29
18﹒ 學生參與計畫,CMU100-SR-21,黃俊發(Chun-Fa Huang),本校(含附醫),具治療胰臟癌潛力之中草藥功效評估與藥理作用機制探討,$35000,2011.8.1 ~ 2012.2.29
19﹒ 個別型,CMU100-TC-01,洪東榮(Hung, Dong-Zong),黃俊發(Chun-Fa Huang),本校(含附醫),內質網壓力(ER-stress)標的基因-CHOP表現在金屬鎘所誘發胰島素b-細胞凋亡中所扮演重要角色之研究,$180000,2011.8.1 ~ 2012.7.31
20﹒ 個別型,CCMP100-RD-046,黃俊發(Chun-Fa Huang),蘇奕彰(Yi-chang, Su)、陳雅雯(Ya-Wen Chen)、吳錦景(Chin-Ching Wu),衛福部,以動物模式評估比較硃砂單方及含硃砂之複方中藥對於肝臟和腎臟毒性損傷與安全性研究(2-1),$1000000,2011.7.19 ~ 2011.12.31
21﹒ 學生參與計畫,NSC 100-2815-C-039-024-B,黃俊發(Chun-Fa Huang),科技部,環境汙染物-雙酚A引起肺臟上皮細胞損傷及作用機轉之探討,$47000,2011.7.1 ~ 2012.2.29
22﹒ 學生參與計畫,NSC 100-2815-C-039-023-B,黃俊發(Chun-Fa Huang),科技部,具治療胰臟癌潛力之中草藥功效評估與藥理作用機制探討,$47000,2011.7.1 ~ 2012.2.29
23﹒ 個別型,CMU99-N1-07-1,黃俊發(Chun-Fa Huang),本校(含附醫),甲基汞誘發神經退化與細胞損傷作用機制之研究-探討MAPK蛋白活化於其中所扮演的角色,$350000,2010.10.1 ~ 2011.7.31
24﹒ 學生參與計畫,CMU99-大專-15,黃俊發(Chun-Fa Huang),本校(含附醫),環境毒性重金屬汙染物-鎘(Cadmium)引起神經細胞毒性傷害與其分子作用機制之研究,$35000,2010.8.1 ~ 2011.2.28
25﹒ 個別型,DMR-100-074,陳俊宏(Chun-Hung Chen),黃俊發(Chun-Fa Huang)、陳雅雯(Ya-Wen Chen),附醫院內計畫,以體外及體內試驗模式探討非離子界面活性劑-Polyoxyethylene alkylphenol ether誘發肺臟功能損傷與細胞死亡之分子作用機制,$100000,2010.8.1 ~ 2011.7.31
26﹒ 學生參與計畫,NSC 99-2815-C-039-015-B,黃俊發(Chun-Fa Huang),科技部,環境毒性重金屬汙染物-鎘(Cadmium)引起神經細胞毒性傷害與其分子作用機制之研究,$47000,2010.7.1 ~ 2011.2.28
27﹒ 整合型項下子計畫(主持人),99農科-3.1.3-糧-Z1(4),陳雅雯(Ya-Wen Chen),黃俊發(Chun-Fa Huang)、劉興華(Shing-Hwa Liu),農委會,冬瓜子調節血糖之保健功效研究(二),$669000,2010.2.27 ~ 2010.12.31
28﹒ 個別型,CMU98-N1-19,黃俊發(Chun-Fa Huang),本校(含附醫),環境重金屬污染物-砷引起胰島Β-細胞功能損傷暨細胞凋亡之研究與內質網壓力生成於其中角色之探討,$500000,2009.10.1 ~ 2010.9.30
29﹒ 個別型,NSC 98-2314-B-039-015,黃俊發(Chun-Fa Huang),劉興華(Shing-Hwa Liu)、陳雅雯(Ya-Wen Chen),科技部,環境污染物-鎘對於胰島素分泌功能和葡萄糖代謝/恆定作用之影響及機制探討,$1100000,2009.8.1 ~ 2010.7.31
30﹒ 學生參與計畫,CMU98-大專-32,黃俊發(Chun-Fa Huang),本校(含附醫),甲基汞(METHYLMERCURY, MEHG)引起肺泡上皮細胞傷害與其作用機制之探討,$30000,2009.8.1 ~ 2010.2.28
31﹒ 個別型,DMR-99-165,陳俊宏(Chun-Hung Chen),洪東榮(Hung, Dong-Zong)、黃俊發(Chun-Fa Huang),附醫院內計畫,汞金屬誘發胰臟胰島β-細胞凋亡與內質網壓力生成於其中角色之研究,$100000,2009.8.1 ~ 2010.6.30
32﹒ 學生參與計畫,NSC 98-2815-C-039-032-B,黃俊發(Chun-Fa Huang),科技部,甲基汞(METHYLMERCURY, MEHG)引起肺泡上皮細胞傷害與其作用機制之探討,$47000,2009.7.1 ~ 2010.2.28
33﹒ 個別型,98農科-3.1.3-糧-Z1(10),陳雅雯(Ya-Wen Chen),黃俊發(Chun-Fa Huang),農委會,開發保健食品計畫--冬瓜調節血糖之保健功效研究,$600000,2009.2.26 ~ 2009.12.31
34﹒ 個別型,CMU97-211,黃俊發(Chun-Fa Huang),本校(含附醫),傳統中草藥-冬瓜子(SEMEN BENINCASAE)萃取物調節血糖和促進胰島素分泌作用機制之研究,$500000,2008.8.1 ~ 2009.6.30
 
獲獎/Award
(獲獎名稱,給獎單位,獲獎日期)
1﹒ 第22屆生物醫學聯合學術會議優秀學術壁報論文獎,中華民國毒物學學會,2008.03.29