學術研究成果/Publication
基本資料/Profiles
姓名/Name: 劉德模 性別/Gender:
英文姓名/
English Name:
De-Meral Liou 英文縮寫/
Abbreviation:
任職單位/
Affiliation:
1.牙醫學院牙醫學系(兼任教授) / School of Dentistry (Part-Time Professor)
2.中國附醫牙醫部牙周病科(兼任醫師) / Division of Periodontics (Adjunct Physician)
3.北港醫院牙科(主任) / ()
Email: spiderdm@yahoo.com
研究專長/Fields of Specialty
1﹒ Stem Cell and Regenerative Medicine
2﹒ Neuroplasticity
3﹒ Nitric Oxide and Acute Lung Injury
4﹒ Fat Embolism Syndrome
5﹒ Olfactory Ensheathing Cell in Neurodegenerative Diseases
6﹒ Periodontal Regeneration
7﹒ Insulin-producing cell in Type I Diabetic
 
期刊論文/Journal Paper
(作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄)
SCI論文 詹子民(Tzu-Min Chan)、(Julia Yi-Ru Chen)、(Li-Ing Ho)、(Hui-Ping Lin)、(Kuo-Wei Hsueh)、劉德模(Demeral David Liu)、(Yi-Hung Chen)、(An-Cheng Hsieh)、(Nu-Man Tsai)、(Dueng-Yuan Hueng)、(Sheng-Tzeng Tsai)、(Pei-Wen Chou)、林欣榮(Shinn-Zong Lin)*、韓鴻志(Horng-Jyh Harn)*,ADSC Therapy in Neurodegenerative Disorders,CELL TRANSPLANTATION,2014 Jan,23(2-3):549-557
SCI論文 (Hsin-Yi Huan)、劉德模(Demeral David Liu)、(Hui-Fen Chang)、(Wu-Fu Chen)、(Hui-Ru Hsu)、(Jon-Son Kuo)、(Mei-Jen Wang)*,Histone Deacetylase Inhibition Mediates Urocortin-Induced Anti-proliferation and Neuronal Differentiation in Neural Stem Cells,STEM CELLS,2012 Dec,30():2760-2773
SCI論文 劉詩平(Shih-Ping Liu)、李信達(Shin-Da Lee)、(Hsu-Tung Lee)、劉德模(Demeral David Liu)、王孝榮(Hsiao-Jung Wang)、(Ren-Shyan Liu)、林欣榮(Shinn-Zong Lin)、徐偉成(Woei-Cherng Shyu)*,Granulocyte Colony-Stimulating Factor Activating HIF-1a Acts Synergistically with Erythropoietin to Promote Tissue Plasticity,PLoS One,2010 Apr,5(4):e10093-1-13
SCI論文 邱紹智(Shao-Chih Chiu)、洪慧珊(Huey-Shan Hung)、林欣榮(Shinn-Zong Lin)、(Esheral Chiang)、劉德模(Demeral David Liu)*,Therapeutic potential of olfactory ensheathing cells in neurodegenerative diseases,JOURNAL OF MOLECULAR MEDICINE-JMM,2009 Sep,87(12):1179-1189
SCI論文 劉德模(Demeral David Liu)、(Lin HI)、謝楠光、陳幸一*,Enhancement Effects of Hypercapnia on the,CHINESE JOURNAL OF PHYSIOLOGY,2009 May,52(3):115-127
SCI論文 劉德模(Demeral David Liu)、高尚志(Kuo SJ)、陳幸一(Chen HI)*,N-Acetylcystein attenuate acute lung injury induced by fat embolism,CRITICAL CARE MEDICINE,2008 Dec,36(2):565-571
SCI論文 劉德模(Demeral David Liu)、謝楠光(Hiseh NK)、陳幸一(Chen HI)*,Histopathological and biochemical changes following fat embolism with adminstration of corn oil micelles,JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME,2008 Nov,90-B(11):1517-1521
SCI論文 徐偉成(Woei-Cherng Shyu)、劉德模(Demeral David Liu)*、林欣榮(Shinn-Zong Lin)、李雯雯(Wen-Wen Li)、蘇靜媛(Cing-Yun Su)、張殷誠(Ying-Chen Chang)、王孝榮(Hsiao-Jung Wang)、王興萬(Hsing-Won Wang)、蔡長海(Chang-Hai Tsai)、李鴻(HUNG LI)*,Implantation of olfactory ensheathing cells promotes neuroplasticity in murine models of stroke,JOURNAL OF CLINICAL INVESTIGATION,2008 Jul,118(7):2482-2495
SCI論文 (Yang YL)、劉德模(Demeral David Liu)、(Hsieh NK)、(Chen HI)*,Endothelin and Gelatinases in Renal Changes Following Blockade of Nitric Oxide Synthase in Hypertensive Rats,CHINESE JOURNAL OF PHYSIOLOGY,2008 Jul,51(3):186-195
SCI論文 (Kuo SJ)、劉德模(Demeral David Liu)、(Chen HI)*,Niacinamide abrogates the organ dysfunction and acute lung injury caused by endotoxin,JOURNAL OF CARDIOVASCULAR PHARMACOLOGY,2008 Feb,50(0):333-342
SCI論文 (Chung IC)、劉德模(Demeral David Liu)、(Kuo SJ)、(Chen HI)*,N-acetylcysteine attenuates the acute lung injury caused by phorbol myristate acetate in isolated rat lungs,PULMONARY PHARMACOLOGY & THERAPEUTICS,2007 Dec,20(0):726-733
SCI論文 (Su CF)、劉德模(Demeral David Liu)、(Kuo SJ)、(Chen HI)*,Nicotinamide abrogates acute lung injury caused by ischaemia/reperfusion,EUROPEAN RESPIRATORY JOURNAL,2007 May,30():199-204
SCI論文 (Chiu CH)、劉德模(Demeral David Liu)、(Hsu YH)、(Lee KC)、(Chen HI)*,Propofol exerts protective effects on the acute lung injury induced by endotoxin in rats,PULMONARY PHARMACOLOGY & THERAPEUTICS,2007 Feb,20(0):503-512
SCI論文 劉德模(Demeral David Liu)、(Hsu YH)、Chen HI*,The endotoxin-induced lung injury is enhanced in rats with spontaneous hypertension,CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY,2007 Jan,34(0):61-69
SCI論文 (Kuo SJ)、劉德模(Demeral David Liu)、(Chen HI)*,Endotoxin-induced lung injury and organ dysfunction are attenuated by pentobarbital anesthesia,CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY,2007 Jan,34(0):480-487
SCI論文 劉德模(Demeral David Liu)、徐偉成、林欣榮(Shinn-Zong Lin)*,Stem cell therapy in stroke: strategies in basic study and clinical application.,ACTA NEUROCHIRURGICA,2006 Dec,Supplement(99):137-139
SCI論文 徐偉成、林欣榮(Shinn-Zong Lin)、(Chau-Chin Lee)、劉德模(Demeral David Liu)、李鴻(Hung Li)*,Granulocyte colony-stimulating factor for acute ischemic stroke: a randomized controlled trial,CANADIAN MEDICAL ASSOCIATION JOURNAL,2006 Mar,174(7):927-933
SCI論文 (Dai NT)、(Yeh MK)、劉德模(Demeral David Liu)、(Adams EF)、(Chiang CH)、(Yen CY)、(Coomes AG)*,A co-culture skin model based on cell support membranes,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2005 Feb,329(0):905-908
SCI論文 謝文雅(Hsieh WY)、(Hsieh YL,)、劉德模(Demeral David Liu)、(Yang SN)、(Wu JN)*,Neural progenitor cells resist excitatory amino acid-induced neurotoxicity,JOURNAL OF NEUROSCIENCE RESEARCH,2003 Mar,71(0):272-278
 
研討會論文/Conference Papers
(發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目)
1﹒ ,XXVth International Symposium on Cerebral Blood Flow, Metabolism, & Function, and Xth International,西班牙巴塞隆納,2011.5.24 ~ 2011.5.28,Stem cell therapy in stable stroke patients
2﹒ ,中華民國中西結合神經醫學會第三屆第二次會員大會暨學術研討會,善導教育中心6樓,2010.12.5 ~ 2010.12.5,漸凍人的幹細胞基因療法
3﹒ ,2010細胞暨組織產品及人體器官保存庫之台北國際研討會,台大醫院國際會議中心,2010.10.13 ~ 2010.10.14,CD34 stem cell intracranial transplantation in treating stable stroke patients: a randomized, controlled phase II trial
4﹒ ,World Forum on Cerebral Blood Flow Metabolism & Function,日本京都,2010.10.18 ~ 2010.10.20,Stem cell therapy in chronic stroke patients-Phase II trial
5﹒ ,2010第二屆國際幹細胞與再生醫學研討會,陽明大學國際會議中心,2010.9.24 ~ 2010.9.25,CD34 stem cell intracranial transplantation in treating stable stroke patients a randomized, controlled phase II trial
6﹒ ,第一屆第二次台灣立體定位功能性神經外科及放射手術學會年會 暨第四屆亞洲區加馬刀研討會,台北晶華酒店,2010.9.18 ~ 2010.9.19,CD34 stem cell intracranial transplantation in treating stable stroke patients: a randomized, controlled phase II trial
7﹒ ,2010 The 7th Asia Pacific Symposium on Neural Regeneration,Yonsei University, Seoul , Korea,2010.9.17 ~ 2010.9.18,CD34 stem cell intracranial transplantation in treating stable stroke patients: a randomized, controlled phase II trial
8﹒ ,第二屆海峽兩岸暨國際神經外科論壇,中國廣州,2010.9.25 ~ 2010.9.26,CD34 stem cell intracranial transplantation in treating stable stroke patients a randomized, controlled phase II trial
9﹒ ,第一屆台灣醫學美容、微整形、抗衰老及生髮醫學聯合學術論壇,台灣台北財團法人張榮發基金會10樓國際會議中心,2010.6.20 ~ 2010.6.20,
10﹒ ,2010年國防醫學院第八屆世界校友會暨國際生物醫學研究及管理會議,香港尖沙嘴龍堡國際賓館,2010.6.5 ~ 2010.6.7,A clinical trial of the treatment of stroke with cord blood stem cells
11﹒ ,國際神經修復學會第三屆年會(3rd International Association of Neurorestoratology),中國北京,2010.4.23 ~ 2010.4.25,CD34 stem cell implantation enables the regeneration of the corticospinal tract in the chronic stroke patients
12﹒ ,幹細胞及神經損傷之再生醫療國際研討會,花蓮慈濟醫院協力樓一樓協力講堂,2010.4.22 ~ 2010.4.24,CD34 stem cell implantation enables the regeneration of the corticospinal tract in the chronic strok
13﹒ ,第三屆泛太平洋國際幹細胞研討會(3rd Pan Pacific Symposium on Stem Cells Research 2010),台中長榮桂冠酒店,2010.4.16 ~ 2010.4.19,CD34 stem cell implantation enables the regeneration of the corticospinal tract in the chronic stroke patients
14﹒ ,國際外科學會中華民國總會專題演講-外科學籍醫療人文最新發展討論會,台北民總醫院致德樓第十會議室,2009.11.1 ~ 2009.11.1,Stem cells therapy in neurological diseases
15﹒ How Stem Cells Make the Corticospinal Tract Regenerated in Stroke Patients,The XIV World Congress of Neurological Surgery of the World Federation of Neurosurgical Societies (W,美國波士頓,2009.8.30 ~ 2009.9.4,
16﹒ ,2009 IMEC-NSoC-TWEMBA Workshop on Bio-medical Electronics,國立交通大學國際會議中心,2009.3.26 ~ 2009.3.26,Stem cells therapy in stroke
17﹒ ,Asian Australasian Society of Stereotactic and Functional Neurosurgery (AASSFN),香港威爾斯親王醫院深造大樓,2009.1.8 ~ 2009.1.10,How Stem Cells Make the Corticospinal Tract
18﹒ ,中華民國中西結合神經醫學會第二屆第三次會員大會暨學術研討會,國立台灣師範大學綜合大樓5樓國際會議廳,2009.1.11 ~ 2009.1.11,How stem cells make corticospinal tract regenerated in stroke patients
19﹒ ,Asian Australasian Society of Stereotactic and Functional Neurosurgery,香港威爾斯親王醫院,2009.1.8 ~ 2009.1.10,How stem cells make the corticospinal tract regenerated in stroke
20﹒ Upregulation of SDF1/CXCR4 promotes neuroplasticity through enhancing PRPc-mediated neuritogenesis in hOEC/ONF-implanted stroke model,ASNTR,Clear Water, USA,2008.6.1 ~ 2008.6.5,
21﹒ ,1st Pan Pacific Symposium,Taichung, Taiwan,2008.5.31 ~ 2008.6.2,OEC transplantation treatmetn in spinal cord injury and stroke
 
研究計畫/Research Grant
(研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,研究經費,計畫期間)
1﹒ 個別型,NSC-2314-B-039-011,劉德模(Demeral David Liu),科技部,探討人嗅鞘細胞於脊髓損傷模式之神經再生機轉,$1000000,2011.8.1 ~ 2012.7.31
2﹒ 個別型,DMR-100-036,劉德模(Demeral David Liu),附醫院內計畫,移植嗅鞘細胞可增強SDF-1α/CXCR4 作用進而加強骨髓幹細胞慕集促進糖尿病鼠胰島再生及回復胰島素功能之研究,$300000,2010.8.1 ~ 2011.7.31
3﹒ 個別型,NSC97-2321-B-039-001-MY2,劉德模(Demeral David Liu),徐偉成(Woei-Cherng Shyu),科技部,從鼻息肉手術檢體分離、培養人類嗅覺鞘細胞及神經幹細胞、暨其對缺氧壓力下神經順商模式之神經再生研究,$1130000,2009.8.1 ~ 2010.7.31
4﹒ 個別型,CMU98-S-39,劉德模(Demeral David Liu),本校(含附醫),移植人類週邊嗅鞘膜細胞於脊髓損傷鼠能促進軸突再生仍藉由向上調控 SDF-1A及加強CXR4與PRPC交互作用機轉之研究,$320000,2009.8.1 ~ 2010.7.31
5﹒ 個別型,DMR-99-038,劉德模(Demeral David Liu),附醫院內計畫,移植神經幹細胞誘導分化之insulin producing cells於糖尿病鼠胰島再生β細胞及回復胰島素功能之研究,$250000,2009.8.1 ~ 2010.7.31
 
專利/Patent
(專利名稱,專利類別,專利國別,專利號碼,專利期間)
1﹒ Pluripotent Olfactory Stem Cells,發明專利,美國,8329166,2012.12.11 ~ 2032.12.11
2﹒ 多能嗅覺幹細胞,發明專利,台灣,I313301,2009.8.11 ~ 2026.1.9
 
獲獎/Award
(獲獎名稱,給獎單位,獲獎日期)
1﹒ 年度優秀論文獎,財團法人腦血管疾病防治基金會,2009.12.19